272451-65-7

Basic information

• Product Name: FLUBENDIAMIDE
• Synonyms: FLUBENDIAMIDE;N2-[1,1-Dimethyl-2-(methylsulfonyl)ethyl]-3-iodo-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}-1,2-benzenedicarboxamide;3-Iodo-N-(2-methanesulfonyl-1,1-dmethylethyl)-N'-(2-methyl-4-(1,2,2,2-tetrafluoro-1-trifluoromethylethyl)phenyl)phthalamide;Flubendiamide [iso];3-Iodo-N2-(2-methyl-1-(methylsulfonyl)propan-2-yl)-N1-(2-methyl-4-(perfluoropropan-2-yl)phenyl)ph;3-Iodo-N2-(2-methyl-1-(methylsulfonyl)propan-2-yl)-N1-(2-methyl-4-(perfluoropropan-2-yl)phenyl)phthalamide;3-Iodo-N2-(2-methyl-1-(methylsulfonyl)propan-2-yl)-N1-(2-methyl-4-(perfluoropropan-2-yl)phenyl;Flubendiamide Solution, 1000ppm
• CAS NO: 272451-65-7
• Molecular Formula: C₂₃H₂₂F₇IN₂O₄S
• Molecular Weight: 682.4
• Product Categories: Agro-Products;pesticide
• Mol File: 272451-65-7.mol

Chemical Properties

• Melting Point: 218-221 °C
• Boiling Point: 578.6oC at 760 mmHg
• Flash Point: 303.7oC
• Appearance: /
• Density: 1.615g/cm3
• Vapor Pressure: 2.2E-13mmHg at 25°C
• Refractive Index: 1.539
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 11.59±0.70(Predicted)
• CAS DataBase Reference: FLUBENDIAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: FLUBENDIAMIDE(272451-65-7)
• EPA Substance Registry System: FLUBENDIAMIDE(272451-65-7)

Safety Data

• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 1
• Hazardous Substances Data: 272451-65-7(Hazardous Substances Data)

Usage

Uses

Used in Agriculture:
Flubendiamide is used as an insecticide for controlling lepidopterous pests in tomato and other crops, providing effective protection against these insects.
Used in Analytical Chemistry:
Flubendiamide is used as an analytical reference standard for determining its presence in vegetables and fruits. It is utilized in high-performance liquid chromatography coupled with ultraviolet detection (HPLC-UV) and HPLC combined with tandem mass spectrometry (MS/MS) to ensure the safety and quality of the produce.

InChI:InChI=1/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)

Synthetic route

3-iodo-N1-(2-methyl-4-heptafluoroisopropylphenyl)-N2-(1,1-dimethyl-2-methylsulfonylethyl)-1,2-benzene formamide (272451-69-1, 272454-80-5, 272454-81-6) → flubendiamide (272451-65-7)

Conditions	Yield
With formic acid; sulfuric acid; dihydrogen peroxide In water; 1,2-dichloro-ethane at 60℃; for 1 - 3h; Product distribution / selectivity;
With formic acid; sulfuric acid; dihydrogen peroxide In water; toluene at 60℃; for 4h; Product distribution / selectivity;
With formic acid; sulfuric acid; dihydrogen peroxide In N,N-dimethyl acetamide; water; chlorobenzene at 70℃; for 3h; Product distribution / selectivity;
With formic acid; sulfuric acid; dihydrogen peroxide In water; chlorobenzene at 80℃; for 3h; Product distribution / selectivity;

Upstream product

• 272451-69-1 3-iodo-N₁-(2-methyl-4-heptafluoroisopropylphenyl)-N₂-(1,1-dimethyl-2-methylsulfonylethyl)-1,2-benzene formamide 

Relevant articles and documents

PROCESS FOR PRODUCING 2-HALOGENOBENZAMIDE COMPOUND

A novel process for producing a 2-halogenobenzamide compound useful as a raw material or active ingredient for medicines and agricultural chemicals. The process, which is for producing a 2-halogenobenzamide compound represented by the general formula (I): (wherein R1, R2, R3, R4, and R6 may be the same or different and each represents hydrogen or C1-6 alkyl; R5 represents C1-6 alkyl; k is 1 or 2; Y1, Y2, Y3, and Y4 may be the same or different and each represents hydrogen, halogeno, etc.; and X represents chlorine, bromine, or iodine), is characterized by reacting an benzamide compound with a halogenating agent in the presence of a palladium catalyst to obtain a substituted benzamide compound and then reacting the resultant substituted benzamide compound with an oxidizing agent after or without isolating the substituted benzamide compound.