27246-88-4 Usage
Uses
Used in Medicinal Chemistry:
(2E)-1-(4-bromophenyl)-2-(4-fluorobenzylidene)hydrazine is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications, particularly in the treatment of diseases that require novel chemical entities for effective management.
Used in Material Science:
In the field of material science, (2E)-1-(4-bromophenyl)-2-(4-fluorobenzylidene)hydrazine is employed as a building block for the creation of new materials with specific properties. Its incorporation into polymers, for instance, can lead to materials with tailored characteristics, such as improved thermal stability or enhanced electrical conductivity, depending on the desired application.
Check Digit Verification of cas no
The CAS Registry Mumber 27246-88-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,4 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 27246-88:
(7*2)+(6*7)+(5*2)+(4*4)+(3*6)+(2*8)+(1*8)=124
124 % 10 = 4
So 27246-88-4 is a valid CAS Registry Number.
27246-88-4Relevant articles and documents
Synthesis of hybrid polycycles containing fused hydroxy benzofuran and 1H-indazoles via a domino cyclization reaction
Janardhanan, Jith C.,James, Kiran,Puthuvakkal, Anisha,Bhaskaran, Rasmi P.,Suresh, Cherumuttathu H.,Praveen, Vakayil K.,Manoj, Narayanapillai,Babu, Beneesh P.
, p. 10166 - 10175 (2019/07/03)
A stoichiometry controlled domino cyclization reaction of hydrazone and p-benzoquinone to an angularly fused 3H-benzofuro[3,2-e]indazole core with an embedded oxygenated dibenzofuran framework under mild reaction conditions is disclosed. The reaction involves palladium catalyzed 5-hydroxy-1H-indazole formation followed by TFA mediated [3+2] annulation between the in situ formed 5-hydroxy-1H-indazole and p-benzoquinone. The developed method is attractive because of the concomitant formation of two heterocyclic rings with consecutive multiple bond forming events that include two C-C, one C-N and one C-O bonds. Spectroscopic and theoretical studies of the blue emissive benzofuroindazole derivatives have also been described.
