cas 27366-21-8, [(6,7-Dichloro-2-ethyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]acetic acid

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(8-Chloro-3-ethyl-1,4-dihydro-4-oxo-7-quinolyloxy)acetic acid, a product obtained from etacrynic acid and hydroxylamine
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Goerlitzer,Hoebbel
p. 134 - 137
(1981)
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[1-Oxo-2-halo(or hydrogen) indanyloxy]-alkanoic acid
[1-Oxo-2-halo(or hydrogen)indanyloxy(or thio)]-alkanoic acid products and salts, esters and amide derivatives where the indanyl ring may be further substituted with from 2 to 5 nuclear substituents. The [1-oxo-2-haloindanyloxy-(or thio)]alkanoic acids are prepared (1) via the halogenation of a [1-oxoindanyloxy(or thio)]alkanoic acid or (2) via the addition of halogen to a [1-oxoindenyloxy(or thio)]-alkanoic acid. The [1-oxoindanyloxy(or thio)]alkanoic acids are prepared (1) via cyclialkylation of a (2-alkylideneacyl)-phenoxy(or thio)alkanoic acid or (2) via etherification of a hydroxy(or mercapto)-2-alkyl-1-indanone. The [1-oxo-2-halo(or hydrogen)indanyloxy(or thio)]alkanoic acids are diuretics and saluretics. In addition, some of these compounds are also able to maintain the uric acid concentration in the body at pretreatment level or to cause a decrease in uric acid concentration.
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(2008/06/13)

Chemical Properties

Melting Point: 169-171 °C(Solv: acetonitrile (75-05-8))
Boiling Point: 505.3°C at 760 mmHg
Flash Point:259.4°C
Density: 1.432g/cm³
Vapor Pressure: 4.95E-11mmHg at 25°C
PKA: 2.80±0.10(Predicted)
PSA: 63.60000
LogP: 3.22180

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27366-21-8

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Chemical Properties

Melting Point: 169-171 °C(Solv: acetonitrile (75-05-8))

Boiling Point: 505.3°C at 760 mmHg

Flash Point:259.4°C

Density: 1.432g/cm³

Vapor Pressure: 4.95E-11mmHg at 25°C

PKA: 2.80±0.10(Predicted)

PSA: 63.60000

LogP: 3.22180

Global suppliers and manufacturers of 27366-21-8total 1 suppliers on LookChem

Article Database

27366-21-8

Articles about 27366-21-8Total 2 be found

More Articles about upstream products of 27366-21-8

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Chemical Properties

Melting Point: 169-171 °C(Solv: acetonitrile (75-05-8))

Boiling Point: 505.3°C at 760 mmHg

Flash Point:259.4°C

Density: 1.432g/cm3

Vapor Pressure: 4.95E-11mmHg at 25°C

PKA: 2.80±0.10(Predicted)

PSA: 63.60000

LogP: 3.22180

Global suppliers and manufacturers of 27366-21-8total 1 suppliers on LookChem

Density: 1.432g/cm³