275387-76-3 Usage
Uses
Used in Organic Synthesis:
1-Boc-3-ethynyl-3-hydroxypyrrolidine is utilized as a building block in the synthesis of various pharmaceuticals and bioactive molecules. Its presence in the synthesis process is crucial for the creation of complex organic compounds that can have significant applications in the medical and pharmaceutical industries.
Used in Chemical Reactions:
In the field of chemical reactions, 1-Boc-3-ethynyl-3-hydroxypyrrolidine serves as a reagent, particularly for the formation of carbon-carbon bonds through alkynylation reactions. Its ethynyl group plays a pivotal role in these reactions, allowing for the extension of carbon chains and the creation of new molecular frameworks that can be further functionalized or used in the development of novel compounds.
Used in Pharmaceutical Development:
Given its role in organic synthesis and its reactivity in chemical reactions, 1-Boc-3-ethynyl-3-hydroxypyrrolidine is also employed in the development of new pharmaceuticals. Its ability to form stable intermediates and participate in key bond-forming reactions makes it a versatile component in the design and synthesis of potential drug candidates.
Used in Bioactive Molecule Preparation:
1-Boc-3-ethynyl-3-hydroxypyrrolidine is also used in the preparation of bioactive molecules, where its unique structural features can contribute to the biological activity of the final product. This can include molecules with potential applications in therapeutics, diagnostics, or as research tools in biological and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 275387-76-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,5,3,8 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 275387-76:
(8*2)+(7*7)+(6*5)+(5*3)+(4*8)+(3*7)+(2*7)+(1*6)=183
183 % 10 = 3
So 275387-76-3 is a valid CAS Registry Number.
275387-76-3Relevant articles and documents
Substituted alkynyl pyridine compounds and methods of use thereof, and use thereof
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, (2016/10/08)
The invention provides a substituted alkynylpyridine compound with a structure represented by a formula (I) as described in the specification and a pharmaceutically acceptable salt and a medicinal preparation thereof. The compound is used for adjusting activity of protein kinase and adjusting intercellular or intracellular signal response. The invention also relates to a pharmaceutical composition including the compound provided by the invention and a method of applying the pharmaceutical composition in treating mammals, especially in treating highly proliferative diseases of the mankind.
SUBSTITUTED ALKYNYL PYRIDINE COMPOUNDS AND METHODS OF USE
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, (2014/01/07)
The present invention provides novel substituted alkynyl pyridine compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.
Substituted bicyclic derivatives useful as anticancer agents
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, (2008/06/13)
The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R1, R3and R4are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals with administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
