276237-03-7

Basic information

• Product Name: 4-(5-PIPERIDIN-4-YL-1,2,4-OXADIAZOL-3-YL)PYRIDINE
• Synonyms: 4-[3-(Pyridin-4-yl)-1,2,4-oxadiazol-5-yl]piperidine, 5-(Piperidin-4-yl)-3-(pyridin-4-yl)-1,2,4-oxadiazole
• CAS NO: 276237-03-7
• Molecular Formula: C₁₂H₁₄N₄O
• Molecular Weight: 230.27
• Mol File: 276237-03-7.mol

Chemical Properties

• Melting Point: 82～85℃
• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 4-(5-PIPERIDIN-4-YL-1,2,4-OXADIAZOL-3-YL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-PIPERIDIN-4-YL-1,2,4-OXADIAZOL-3-YL)PYRIDINE(276237-03-7)
• EPA Substance Registry System: 4-(5-PIPERIDIN-4-YL-1,2,4-OXADIAZOL-3-YL)PYRIDINE(276237-03-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 276237-03-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
4-(5-Piperidin-4-yl-1,2,4-oxidiazol-3-yl)pyridine is used as a chemical intermediate for the development of new pharmaceutical compounds. Its unique structure, combining pyridine and oxadiazole rings, may offer novel properties that can be exploited in the design of drugs with specific therapeutic targets.
Used in Chemical Synthesis:
In the chemical industry, 4-(5-Piperidin-4-yl-1,2,4-oxidiazol-3-yl)pyridine is used as a key component in the synthesis of more complex molecules. Its presence in the Piperidine family suggests that it could be a valuable building block for creating a variety of chemical products, including potential applications in materials science and specialty chemicals.
Used in Pesticide Formulation:
Given the widespread use of pyridine in the production of pesticides, 4-(5-Piperidin-4-yl-1,2,4-oxidiazol-3-yl)pyridine may be used as an active ingredient or a precursor in the formulation of new pesticides. Its potential role in this industry could be to enhance the effectiveness of existing products or to develop novel compounds with improved properties, such as increased selectivity or reduced environmental impact.
Used in Dye Production:
As pyridine is also a key component in the synthesis of dyes, 4-(5-Piperidin-4-yl-1,2,4-oxidiazol-3-yl)pyridine could be utilized in the development of new dye formulations. Its incorporation into dye molecules may lead to the creation of dyes with unique color properties or improved stability, which could be beneficial in various applications, such as textiles, printing, and art materials.

Upstream product

• 74901-69-2 2,4-dichloro-6,7-dihydro-thieno[3,2-d]pyrimidine 
• 1143575-83-0 (R)-2-(2-chloro-5-oxo-6,7-dihydro-5H-5λ⁴-thieno[3,2-d]pyrimidin-4-ylamino)-3-methyl-butan-1-ol 
• 1143575-82-9 (R)-2-(2-chloro-6,7-dihydro-thieno[3,2-d]pyrimidin-4-ylamino)-3-methyl-butan-1-ol 

Relevant articles and documents

DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS

The present invention relates to new drug combinations which contain in addition to one or more PDE4-inhibitors at least one NSAID (=non-steroidal anti-inflammatory drug) (2), processes for preparing them and their use in treating in particular respiratory complaints such as for example COPD, chronic sinusitis and asthma. The invention particularly relates to those drug combinations which contain, in addition to one or more, preferably one PDE4 inhibitor of general formula 1 wherein X is SO or SO2, but preferably SO, and wherein R1, R2, R3 and R4 have the meanings given in claim 1, at least one NSAID (2), the preparation thereof and the use thereof for the treatment of respiratory complaints.

HETEROCYCLIC DERIVATIVES AS GPCR RECEPTOR AGONISTS

Compounds of Formula (I), R1-A-V-B-R2; or pharmaceutically acceptable salts thereof, are agonists of GPR116 and are useful as regulators of satiety, e.g. for the treatment of obesity, and for the treatment of diabetes.