276694-22-5

Basic information

• Product Name: [4-(1,3,4-OXADIAZOL-2-YL)PHENYL]BORONIC ACID
• Synonyms: [4-(1,3,4-OXADIAZOL-2-YL)PHENYL]BORONIC ACID
• CAS NO: 276694-22-5
• Molecular Formula: C₈H₇BN₂O₃
• Molecular Weight: 189.965
• Mol File: 276694-22-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [4-(1,3,4-OXADIAZOL-2-YL)PHENYL]BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(1,3,4-OXADIAZOL-2-YL)PHENYL]BORONIC ACID(276694-22-5)
• EPA Substance Registry System: [4-(1,3,4-OXADIAZOL-2-YL)PHENYL]BORONIC ACID(276694-22-5)

Safety Data

• Hazardous Substances Data: 276694-22-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
[4-(1,3,4-OXADIAZOL-2-YL)PHENYL]BORONIC ACID is used as a reagent in the Suzuki coupling reaction, which is a widely employed method for forming carbon-carbon bonds. This reaction is crucial in the synthesis of various organic compounds, making this boronic acid derivative an essential component in the field of organic chemistry.
Used in Pharmaceutical Research:
In the pharmaceutical industry, [4-(1,3,4-OXADIAZOL-2-YL)PHENYL]BORONIC ACID serves as a building block for the synthesis of potential pharmaceutical compounds. Its unique structure and reactivity contribute to the development of new drugs with improved properties and therapeutic effects.
Overall, [4-(1,3,4-OXADIAZOL-2-YL)PHENYL]BORONIC ACID is a valuable compound with diverse applications in both the synthesis of organic compounds and the development of new pharmaceuticals, showcasing its importance in the fields of chemistry and medicine.

Upstream product

• 41420-90-0 2-(4-bromophenyl)-1,3,4-oxadiazole 
• 5419-55-6 Triisopropyl borate 
• 121-43-7 Trimethyl borate 
• 7732-18-5 water 
• 589-87-7 1,4-bromoiodobenzene 

Downstream Products

• 1386231-68-0 potassium 4-(1,3,4-oxadiazol-2-yl)phenyltrifluoroborate 

Relevant articles and documents

Aromatic compound and organic electroluminescent device thereof

The invention provides an aromatic compound and an organic electroluminescent device thereof, and relates to the technical field of organic photoelectric materials. The aromatic compound has a high glass transition temperature, very high electron transmission ability, good stability and high film forming ability, has proper HOMO (Highest Occupied Molecular Orbital) and LUMO (Lowest Unoccupied Molecular Orbital) values, is used as an electron transmission layer in OLED (Organic Light-Emitting Diode) devices, can effectively reduce the driving voltage of a device, improve the luminous efficiencyand brightness of the device, and prolong the service life of the device, and is a kind of organic electroluminescent material with excellent performance.

Scope of the palladium-catalyzed aryl borylation utilizing bis-boronic acid

The Suzuki-Miyaura reaction has become one of the more useful tools for synthetic organic chemists. Until recently, there did not exist a direct way to make the most important component in the coupling reaction, namely the boronic acid. Current methods to make boronic acids often employ harsh or wasteful reagents to prepare boronic acid derivatives and require additional steps to afford the desired boronic acid. The scope of the previously reported palladium-catalyzed, direct boronic acid synthesis is unveiled, which includes a wide array of synthetically useful aryl electrophiles. It makes use of the newly available second generation Buchwald XPhos preformed palladium catalyst and bis-boronic acid. For ease of isolation and to preserve the often sensitive C-B bond, all boronic acids were readily converted to their more stable trifluoroborate counterparts.

ETHANOLAMINE SALT OF N- (3-METHOXY-5-METHYLPYRAZIN-2YL) -2- (4- [1 , 3 , 4-0XADIAZ0LE-2-YL] PHENYL) PYRIDINE-3- SULPHONAMIDE

N-(Methoxy-5-methylpyrazin-2-yl)-2-(4-[1 ,3,4-oxadiazol-yl]phenyl)pyridine-3- sulphonamide ethanolamine salt its synthesis and its uses are described.

CHEMICAL PROCESS

Process for preparing compounds of Formula (I); and (IV); are described.