277752-98-4Relevant articles and documents
A novel synthesis of N-hydroxy-3-aroylindoles and 3-aroylindoles
Ieronimo, Gabriella,Palmisano, Giovanni,Maspero, Angelo,Marzorati, Alessandro,Scapinello, Luca,Masciocchi, Norberto,Cravotto, Giancarlo,Barge, Alessandro,Simonetti, Marco,Ameta, Keshav Lalit,Nicholas, Kenneth M.,Penoni, Andrea
supporting information, p. 6853 - 6859 (2018/10/20)
A straightforward indole synthesis via annulation of C-nitrosoaromatics with conjugated terminal alkynones was realised achieving a simple, highly regioselective, atom- and step economical access to 3-aroylindoles in moderate to good yields. Further functionalizations of indole scaffolds were investigated and an easy way to JWH-018, a synthetic cannabinoid, was achieved.
Silver(I)-catalyzed reaction between pyrazole and propargyl acetates: Stereoselective synthesis of the scorpionate ligands (E)-allyl-gem-dipyrazoles (ADPs)
Bhanuchandra,Kuram, Malleswara Rao,Sahoo, Akhila K.
, p. 11824 - 11834 (2014/01/06)
The reaction between readily accessible pyrazole and propargyl acetates in the presence of Ag(I) catalyst yielded a new class of (E)-allyl-gem-dipyrazole scorpionate ligands: 1-aryl-2-N-pyrazolyl allyl acetates and 1,3-dipyrazolyl-3-arylpropene. The reaction showed broad substrate scope, and various functional and protecting groups were tolerated under the reaction conditions. The palladium(II) scorpionate complex could thus be easily prepared and successfully employed in Suzuki-Miyaura cross-couplings in water.
Catalytic decarboxylation of 2-alkynoic acids
Kolarovic, Andrej,Faberova, Zuzana
experimental part, p. 7199 - 7202 (2009/12/09)
(Chemical Equation Presented) A very efficient protocol enabling catalytic decarboxylation of a wide range of 2-alkynoic acids is described. The reaction conditions and the scope of the process are examined. The method is further utilized in a model decar
Efficient synthesis of rotaxane based on complexation of acetylene and dicobalt hexacarbonyl: Introduction of a transformable functional group
Tokunaga, Yuji,Ohta, Go,Yamauchi, Yuji,Goda, Tatsuhiro,Kawai, Nobuhiko,Sugihara, Takumichi,Shimomura, Youji
, p. 766 - 767 (2007/10/03)
An efficient end-capping method for preparation of rotaxanes by complexation of dicobalt hexacarbonyl and acetylene moiety of the axle end is described here. The end-capping reaction of pseudorotaxanes proceeds under mild conditions and furnishes the expected rotaxanes bearing a transformable functional group in high yield. Copyright
Functionalised alkenylcarbene metal complexes (M=Ru, W, Cr) by activation of propargyl alcohol derivatives
Ulrich, Karine,Porhiel, Emmanuel,Péron, Vincent,Ferrand, Vincent,Le Bozec, Hubert
, p. 78 - 86 (2007/10/03)
The reaction of arene ruthenium(II) complexes [Ru(η6-C6Me4R2)(PMe 3)Cl2] (1, R=Me; 1′, R=H) with propargyl alcohol derivatives HCC(H)(OH)(p-C6H4-X) (a, X=HCC(H)(OH); c, X=CHO; d, X=CH=CH2; e, X=CH=CH-CH=CH2) and methanol gives the (methoxy)-alkenylcarbene ruthenium complexes [Ru(η6-C6Me4R2)(PMe 3)(Cl) (=C(OMe)(CH=CH-p-C6H4-X)][PF6] (2a) and (2′c-e). Similarly, the half-sandwich carbene complexes [Ru(η5-C5H5)(CO)(PPh 3)(=C(OMe)(CH=CH-p-C6H4-X)][BF4] (4a and 4d) are obtained from [Ru(η5-C5H5)(CO)(PPh3)(Cl)] (3) and propargyl alcohol derivatives a and d, respectively. Treatment of M(CO)5(THF) (M=W, Cr) with a and HCC(H)(OH)-C4H2S-(OH)(H)CCH (b) yields the monometallic complexes (CO)5M=C(OMe)(=C(OMe)(CH=CH-Ar-(OH)(H)CCH)] (5a) (M=W; -Ar-=-C6H4-), 5b (M=W; -Ar-=-C4H2S-), and 7a (M=Cr; -Ar-=-C6H4-) as the major products, and the bimetallic complexes (CO)5W=C(OMe)CH=CH-Ar-CH=CH(OMe)C=W(CO)5 (6a) and (6b) as the minor products. Finally, the reaction of 5a and 5b with amines (iPrNH2, Me2NH, Et2NH), and diamines such as ethylene diamine and piperazine produces the expected amino alkenyl-tungsten complexes 9a-13a and 9b in high yields.
