27848-81-3Relevant articles and documents
Preparation of (R)-(+)-Lithium Lactate
Cervantes-Cuevas,Joseph-Nathan
, p. 201 - 206 (2007/10/03)
Optically pure (R)-(+)-lithium lactate (7) and its benzyl ether analogue (6a) were obtained from acetaldehyde using Eliel's 1,3-trans-oxathiane (1) as the chiral auxiliary for chromatographic separation.
Complete conversion of l-lactate into d-lactate. A generic approach involving enzymatic catalysis, electrochemical oxidation of NADH, and electrochemical reduction of pyruvate
Biade, Azz-Eddine,Bourdillon, Christian,Laval, Jean-Marc,Mairesse, Gilles,Moiroux, Jacques
, p. 893 - 897 (2007/10/02)
L-Lactate was converted into D-lactate with a yield better than 97%, the system involving stereospecific catalysis of L-lactate oxidation by the rather cheap L-lactate dehydrogenase plus electrochemical regeneration of NAD+ at the anode and electrochemical reduction of pyruvate at the cathode. Such an approach can be extended to mere deracemization or complete inversion of all types of chiral α-alcohol-acids provided that the dehydrogenase related to the isomer to be inverted is available. Efficiency was not limited by enzyme or coenzyme deactivations.