278782-13-1

Basic information

• Product Name: 4,5-DIHYDRO-NAPHTHO[1,2-B]THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE
• Synonyms: 4,5-DIHYDRONAPHTHO[1,2-B]THIOPHENE-2-CARBOHYDRAZIDE;4,5-DIHYDRO-NAPHTHO[1,2-B]THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE
• CAS NO: 278782-13-1
• Molecular Formula: C13H12N2OS
• Molecular Weight: 244.31
• Mol File: 278782-13-1.mol

Chemical Properties

• Melting Point: 162-165°C
• Appearance: /
• Density: 1.334±0.06 g/cm3(Predicted)
• PKA: 12.36±0.20(Predicted)
• CAS DataBase Reference: 4,5-DIHYDRO-NAPHTHO[1,2-B]THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIHYDRO-NAPHTHO[1,2-B]THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE(278782-13-1)
• EPA Substance Registry System: 4,5-DIHYDRO-NAPHTHO[1,2-B]THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE(278782-13-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 278782-13-1(Hazardous Substances Data)

Upstream product

• 320423-96-9 methyl 4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate 

Relevant articles and documents

A Schiff base sensor for relay monitoring of In3+and Fe3+through “off-on-off” fluorescent signals

A Schiff baseN′-(3-ethoxy-2-hydroxybenzylidene)-4,5-dihydronaphtho[1,2-b]thiophene-2-carbohydrazide (LB2) was designed and synthesized based on 4,5-dihydronaphtho[1,2-b]thiophene-2-carbohydrazide and 3-ethoxy-2-hydroxybenzaldehyde, and could be used as a sensor to identify In3+and Fe3+through fluorescence ‘off-on-off’ behavior. The probeLB2showed high sensitivity and selectivity towards In3+and Fe3+in the presence of other metal ions with detection limits of 8.05 × 10?9M and 2.59 × 10?8M, respectively. The structure ofLB2was characterized by1H NMR,13C NMR, FTIR and mass spectrometry. The complexation ratio ofLB2to In3+and Fe3+was 1?:?1 for both which was verified by mass spectrometry and the Job plot. The binding mode and sensing mechanism ofLB2with In3+and Fe3+were also verified.

A multifunctional selective fluorescent chemosensor for detection of Ga3+, In3+ and Fe3+ in different solvents

A new fluorescent sensor, (E)-N'-((3-hydroxypyridin-2-yl)methylene)-4,5-dihydronaphtho[1,2-b]thiophene-2-carbohydrazide (LB3), was designed and synthesized based on 4,5-dihydronaphtho[1,2-b]thiophene-2-carbohydrazide and 3-hydroxypicolinaldehyde. LB3 not only exhibited fluorescence turn-on response towards Ga3+ with a detection limit of 4.42 × 10?9 M in DMSO/H2O (9:1) buffer solution, but also showed fluorescence turn-on response towards In3+ with a detection limit of 1.99 × 10?11 M in the DMF/H2O (9:1) buffer solution and the new formed complex LB3[In3+] could be further employed as the turn-off response towards Fe3+ with a detection limit of 1.67 × 10?8 M. Moreover, LB3 showed high sensitivity and selectivity towards Ga3+, In3+ and Fe3+ in the presence of other metal ions. The complexation ratio of LB3 to Ga3+, In3+ and Fe3+ were 1: 2, which were testified by mass spectrometry and the Job's plot. The structure of LB3 was performed by 1H NMR, 13C NMR, FTIR and mass spectrum.