27912-16-9

Basic information

• Product Name: 1,2,4,5-TETRAHYDRO-BENZO[D]AZEPINE-3-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 1,2,4,5-TETRAHYDRO-BENZO[D]AZEPINE-3-CARBOXYLIC ACID METHYL ESTER
• CAS NO: 27912-16-9
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.253
• Mol File: 27912-16-9.mol

Chemical Properties

• Boiling Point: 320.0±31.0 °C(Predicted)
• Appearance: /
• Density: 1.123±0.06 g/cm3(Predicted)
• PKA: -1.52±0.20(Predicted)
• CAS DataBase Reference: 1,2,4,5-TETRAHYDRO-BENZO[D]AZEPINE-3-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4,5-TETRAHYDRO-BENZO[D]AZEPINE-3-CARBOXYLIC ACID METHYL ESTER(27912-16-9)
• EPA Substance Registry System: 1,2,4,5-TETRAHYDRO-BENZO[D]AZEPINE-3-CARBOXYLIC ACID METHYL ESTER(27912-16-9)

Safety Data

• Hazardous Substances Data: 27912-16-9(Hazardous Substances Data)

Usage

Chemical class

Belongs to the class of benzodiazepines.

Structure

Methyl ester derivative of the carboxylic acid compound with a tetrahydrobenzazepine ring structure.

Pharmaceutical use

Often used as a precursor in the synthesis of various pharmaceutical drugs, particularly those that act on the central nervous system.

Psychoactive effects

Known for its potential psychoactive effects.

Research and development

Studied for its potential use in the treatment of anxiety and other psychological conditions.

Versatility

Has applications in both research and drug development.

Upstream product

• 4424-20-8 2,3,4,5-tetrahydro-1H-3-benzazepine 
• 79-22-1 methyl chloroformate 

Downstream Products

• 107393-73-7 2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamine 
• 444588-24-3 methyl 7-amino-2,3,4,5-tetrahydro-1H-3-benzazepine-3-carboxylate 
• 142853-23-4 3-methoxycarbonyl-7-[3-(1-benzoylpiperidin-4-yl)-1-oxopropyl]-2,3,4,5-tetrahydro-1H-3-benzazepine 

Relevant articles and documents

Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials

Novel benzazepine oxazolidinone antibacterials were synthesized and evaluated against clinically relevant susceptible and resistant organisms. The effect of ring nitrogen position and N-substitution on antibacterial activity is examined.

Condensed heterocyclic compounds, their production and use

A condensed heterocyclic derivative of the formula (I): STR1 wherein X is an oxygen atom, a sulfur atom or R1 --N1 is a hydrogen atom, a hydrocarbon group which may be substituted or an acyl group which may be substituted; R2 is a hydrogen atom or a hydrocarbon group which may be substituted; ring A is a benzene ring which may be substituted, k is a whole number of 0 to 3; m is a whole number of 1 to 8; and n is a whole number of 1 to 6, or a pharmaceutically acceptable salt thereof exhibiting high colinesterase inhibitory activity, and a method for producing the same.