279237-85-3

Basic information

• Product Name: 2-(2,4-DiMethyl-1H-iMidazol-1-yl)ethanaMine
• Synonyms: 2-(2,4-DiMethyl-1H-iMidazol-1-yl)ethanaMine
• CAS NO: 279237-85-3
• Molecular Formula: C₇H₁₃N₃
• Molecular Weight: 139.19822
• Mol File: 279237-85-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(2,4-DiMethyl-1H-iMidazol-1-yl)ethanaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4-DiMethyl-1H-iMidazol-1-yl)ethanaMine(279237-85-3)
• EPA Substance Registry System: 2-(2,4-DiMethyl-1H-iMidazol-1-yl)ethanaMine(279237-85-3)

Safety Data

• Hazardous Substances Data: 279237-85-3(Hazardous Substances Data)

Usage

Type of compound

heterocyclic organic compound

Structure

contains an imidazole ring

Uses

building block in the synthesis of pharmaceuticals and other organic compounds

Biological activities

antimicrobial, antiviral, and antifungal properties

Potential uses

treatment of neurological disorders, potential drug candidate for other medical conditions.

Upstream product

• 930-62-1 2,4-Dimethylimidazole 
• 870-24-6 2-chloroethanamine hydrochloride 

Downstream Products

• 279237-37-5 4-(1,1-dimethylethyl) 1-(phenylmethyl)-2(R)-[[[2-(2,4-dimethyl-1H-imidazol-1-yl)ethyl]amino]carbonyl]-1,4-piperazinedicarboxamide 
• 279237-99-9 4-(1,1-dimethylethyl) 1-(phenylmethyl)-2(R)-[[[2-(2,5-dimethyl-1H-imidazol-1-yl)ethyl]amino]carbonyl]-1,4-piperazinedicarboxamide 

Relevant articles and documents

5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES

The invention relates to 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I),wherein X represents CH2 or O; R1 represents a phenyl group, which group is independently mono-, di-, or tri-substituted wherein the substituents are independently selected from the group consisting of (C1-4)alkyl, (C1-4)alkoxy, halogen, cyano, trifluoromethoxy and trifluoromethyl; R2 represents (C1-4)alkyl, (C1-4)alkoxy, (C2-4)alkenyl, halogen, cyano, hydroxymethyl, trifluoromethyl, C(O)NR5R6 or cyclopropyl; R3 represents (C1-4)alkyl, (C1-4)alkoxy-methyl or halogen; R4 represents (C1-4)alkyl; R5 represents hydrogen or (C1-4)alkyl; and R6 represents hydrogen or (C1-4)alkyl. The invention also relates to pharmaceutically acceptable salts of such compounds; and to the use of such compounds as medicaments; especially as orexin receptor antagonists.

PIPERAZINE DERIVATIVES AS FARNESYL PROTEIN TRANSFERASE INHIBITORS

Disclosed are compounds of the formula: wherein R13 represents an imidazole ring; R14 represents a carbamate, urea, amide or sulfonamide group, and the remaining substituents are as defined herein. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.

NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Novel compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl-protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human.