27991-81-7

Basic information

• Product Name: 8-AMinooctanoic acid HCl
• Synonyms: 8-AMinooctanoic acid HCl;8-aminooctanoic acid hydrochloride;8-amino- Octanoic acid- hydrochloride (1:1); 27991-81-7
• CAS NO: 27991-81-7
• Molecular Formula: C8H18ClNO2
• Molecular Weight: 195.68702
• Mol File: 27991-81-7.mol

Chemical Properties

• Melting Point: 144-145 °C
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 8-AMinooctanoic acid HCl(CAS DataBase Reference)
• NIST Chemistry Reference: 8-AMinooctanoic acid HCl(27991-81-7)
• EPA Substance Registry System: 8-AMinooctanoic acid HCl(27991-81-7)

Safety Data

• Hazardous Substances Data: 27991-81-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
8-Aminooctanoic acid HCl is used as a precursor in the synthesis of various bioactive compounds for the development of pharmaceutical products.
Used in Personal Care Industry:
8-Aminooctanoic acid HCl is used as an ingredient in personal care products for its antibacterial and antifungal properties, making it a valuable component in the formulation of topical medications and antiseptic solutions.
Used in Neurodegenerative Disease Treatment:
8-Aminooctanoic acid HCl is used as a potential treatment for neurodegenerative diseases due to its ability to modulate the activity of certain neurotransmitters.

Upstream product

• 82105-71-3 8-methoxycarbonylamino-octanoic acid methyl ester 
• 123-99-9 azelaic acid 
• 1732-10-1 Dimethyl azelate 
• 56555-02-3 methyl 9-chloro-9-oxononanoate 
• 2104-19-0 azelaic monomethyl ester 
• 123865-75-8 Methyl 8-carbamoyloctanoate 
• 1002-57-9 8-Aminooctanoic acid 

Relevant articles and documents

Transkarbams as transdermal permeation enhancers: Effects of ester position and ammonium carbamate formation

Transkarbam 12, an ammonium carbamate formed by the reaction of dodecyl 6-aminohexanoate with carbon dioxide, is a highly active, broad-spectrum, nontoxic, and nonirritant transdermal permeation enhancer. It probably acts by a dual mechanism: a part of its activity is associated with the carbamic acid salt and/or its decomposition in the acidic stratum corneum. The ammonium ester thereby released is an active enhancer species as well, and its activity highly depends on the position of the ester group.

Transformations of higher terpenoids: IV. Synthesis and spectral parameters of glycyrrhetinic acid derivatives containing amino acid fragments

New glycyrrhetinic acid derivatives containing amino acid and amino ester fragments were synthesized as potential biologically active substances. NMR spectra of the newly synthesized compounds were studied, and assignment of signals of the C8 and C14 carbon atoms in the terpenoid fragment was refined.