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CAS

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280762-05-2

8-Azabicyclo[3.2.1]octan-3-amine,N-(2-nitrophenyl)-8-(phenylmethyl)-, (3-exo)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 280762-05-2 Structure

  • Basic information

    1. Product Name: 8-Azabicyclo[3.2.1]octan-3-amine,N-(2-nitrophenyl)-8-(phenylmethyl)-, (3-exo)-
    2. Synonyms: endo-8-benzyl-N-(2-nitrophenyl)-8-aza-bicylo[3.2.1]octan-3- amine;8-Azabicyclo[3.2.1]octan-3-amine, N-(2-nitrophenyl)-8-(phenylmethyl)-, (3-exo)-
    3. CAS NO:280762-05-2
    4. Molecular Formula: C20H23N3O2
    5. Molecular Weight: 337.42
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 280762-05-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 494.5±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.253±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 9.92±0.40(Predicted)
    10. CAS DataBase Reference: 8-Azabicyclo[3.2.1]octan-3-amine,N-(2-nitrophenyl)-8-(phenylmethyl)-, (3-exo)-(CAS DataBase Reference)
    11. NIST Chemistry Reference: 8-Azabicyclo[3.2.1]octan-3-amine,N-(2-nitrophenyl)-8-(phenylmethyl)-, (3-exo)-(280762-05-2)
    12. EPA Substance Registry System: 8-Azabicyclo[3.2.1]octan-3-amine,N-(2-nitrophenyl)-8-(phenylmethyl)-, (3-exo)-(280762-05-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 280762-05-2(Hazardous Substances Data)

280762-05-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 280762-05-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,0,7,6 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 280762-05:
(8*2)+(7*8)+(6*0)+(5*7)+(4*6)+(3*2)+(2*0)+(1*5)=142
142 % 10 = 2
So 280762-05-2 is a valid CAS Registry Number.

280762-05-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name exo-8-benzyl-N-(2-nitrophenyl)-8-azabicyclo[3.2.1]octan-3-amine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:280762-05-2 SDS

280762-05-2Relevant articles and documents

Discovery of bioavailable 4,4-disubstituted piperidines as potent ligands of the chemokine receptor 5 and inhibitors of the human immunodeficiency virus-1

Kazmierski, Wieslaw M.,Aquino, Christopher,Chauder, Brian A.,Deanda, Felix,Ferris, Robert,Jones-Hertzog, Deborah K.,Kenakin, Terrence,Koble, Cecilia S.,Watson, Christian,Wheelan, Pat,Yang, Hanbiao,Youngman, Michael

experimental part, p. 6538 - 6546 (2009/11/30)

We describe robust chemical approaches toward putative CCR5 scaffolds designed in our laboratories. Evaluation of analogues in the 125I-[MIP-1β] binding and Ba-L-HOS antiviral assays resulted in the discovery of 64 and 68 in the 4,4-disubstitited piperidine class H, both potent CCR5 ligands (pIC50 = 8.30 and 9.00, respectively) and HIV-1 inhibitors (pIC50 = 7.80 and 7.84, respectively, in Ba-L-HOS assay). In addition, 64 and 68 were bioavailable in rodents, establishing them as lead molecules for further optimization toward CCR5 clinical candidates.

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