28164-29-6Relevant articles and documents
Polysubstituted Indole Synthesis via Palladium/Norbornene Cooperative Catalysis of Oxime Esters
Liu, Jiechun,Lin, Haojiang,Jiang, Huanfeng,Huang, Liangbin
supporting information, p. 484 - 489 (2022/01/20)
Polysubstituted indoles are prevalent in pharmaceuticals, agrochemicals, and organic materials. Presented herein is the fact that polyfunctionalized indoles can be efficiently constructed from easily accessible oxime esters and aryl iodides, involving a palladium/norbornene synergistic synthesis. The reaction is enabled by a unique class of electrophiles in palladium/norbornene cooperative catalysis, which are oxime esters derived from simple ketone. The broad substrate scope and high functional group tolerance could make this method attractive for the synthesis of polysubstituted indoles.
Cobalt-Catalyzed Chemo- and Enantioselective Hydrogenation of Conjugated Enynes
Hu, Yanhua,Liu, Yangang,Zhang, Wanbin,Zhang, Zhenfeng
supporting information, p. 16989 - 16993 (2021/06/28)
Asymmetric hydrogenation is one of the most powerful methods for the preparation of single enantiomer compounds. However, the chemo- and enantioselective hydrogenation of the relatively inert unsaturated group in substrates possessing multiple unsaturated bonds remains a challenge. We herein report a protocol for the highly chemo- and enantioselective hydrogenation of conjugated enynes while keeping the alkynyl bond intact. Mechanism studies indicate that the accompanying Zn2+ generated from zinc reduction of the CoII complex plays a critical role to initiate a plausible CoI/CoIII catalytic cycle. This approach allows for the highly efficient generation of chiral propargylamines (up to 99.9 % ee and 2000 S/C) and further useful chemical transformations.
USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS V
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Page/Page column 37, (2021/12/31)
The present invention relates to the use of strobilurin-like compounds of formula I and N-oxides and salts thereof to fight against phytopathogenic fungi, containing a substitution of amino acids F129L in the mitochondrial cytochrome b protein (also calle
Cycloisomerization of acetylenic oximes and hydrazones under gold catalysis: Synthesis and cytotoxic evaluation of isoxazoles and pyrazoles
Jeyaveeran,Praveen, Chandrasekar,Arun,M Prince,Perumal
, p. 73 - 83 (2016/02/09)
The synthesis of substituted isoxazoles and pyrazoles through a general cycloisomerization methodology has been reported. The capability of gold(III) chloride to promote cycloisomerization of both α, β-acetylenic oximes and α, β-acetylenic hydrazones is t
Gold(III)-catalyzed synthesis of isoxazoles by cycloisomerization of α,β-acetylenic oximes
Praveen,Kalyanasundaram,Perumal
body text, p. 777 - 781 (2010/06/12)
Cycloisomerization of,-acetylenic oximes leading to substituted isoxazoles was achieved using AuCl3 as catalyst, under moderate reaction conditions. The reaction can be applied to various acetylenic oximes and gives good to excellent yields. Th
Synthesis of isochalcogenazole rings by treating β-(N,N- dimethylcarbamoylchalcogenenyl)alkenyl ketones with hydroxylamine-O-sulfonic acid
Shimada, Kazuaki,Moro-oka, Akiko,Maruyama, Akiko,Fujisawa, Hiroyuki,Saito, Toshio,Kawamura, Ryo,Kogawa, Hisashi,Sakuraba, Maiko,Takata, Yukichi,Aoyagi, Shigenobu,Takikawa, Yuji,Kabuto, Chizuko
, p. 567 - 577 (2008/02/11)
β-(N,N-Dimethylcarbamoylselenenyl)- and β-(N,N- dimethylcarbamoyltellurenyl)alkenyl ketones were converted into isoselenazoles and isotellurazole Te-oxides, respectively, simply by treating with hydroxylamine-O-sulfonic acid, and deoxygenation of the latt
