28168-20-9

Basic information

• Product Name: 2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid methyl ester
• Synonyms: 2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid methyl ester
• CAS NO: 28168-20-9
• Molecular Weight: 215.252
• Mol File: 28168-20-9.mol

Chemical Properties

• CAS DataBase Reference: 2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid methyl ester(28168-20-9)
• EPA Substance Registry System: 2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid methyl ester(28168-20-9)

Safety Data

• Hazardous Substances Data: 28168-20-9(Hazardous Substances Data)

Upstream product

• 70-11-1 α-bromoacetophenone 
• 75519-84-5 3-oxo-2-(2-oxo-2-phenyl-ethyl)-butyric acid methyl ester 
• 14205-39-1 methyl 3-aminocrotonate 
• 536-74-3 phenylacetylene 
• 105-45-3 acetoacetic acid methyl ester 

Relevant articles and documents

Green multicomponent reaction for synthesis of trisubstituted pyrroles in ionic liquid [bmim]BF4

2,4,5-Trisubstituted pyrrole derivatives were efficiently synthesized by one-pot condensation of 1,3-diones, α-bromoacetophenones, and ammonium acetate in ionic liquid [bmim]BF4. The new synthetic method offers multisubstituted pyrroles with th

I2-DMSO promoted metal free oxidative cyclization for the synthesis of substituted Indoles and pyrroles

A series of di substituted indole and tri substituted pyrrole derivatives were synthesized efficiently by using I2/K2CO3 in DMSO. The novel synthesis method offers the advantage of mild reaction conditions, operational simplicity, higher yields. The method is functional group tolerant and provides quick access to medicinally significant compounds in moderate to high yields.

Microwave-assisted facile synthesis of trisubstituted pyrrole derivatives

We report efficient synthesis of pyrrole derivatives by use of microwave irradiation. Quantitative yields were obtained in short reaction times. Low yields of product were obtained from alicyclic amino unsaturated ketone derivatives; higher yields were ob

Infrared heat aided solid state synthesis of pyrroles from 1,4-diketones and ammonium acetate

A facile amination of 1,4-diketones with ammonium acetate has been achieved by mechanochemical grinding assisted by infrared irradiation in the presence of silica gel. The wastes are reduced and the energy resources saved..

Synthesis of substituted pyrroles from N-vinylic phosphazenes derived from β-amino acids and α-bromo ketones

Synthesis of di-, tri- and tetrasubstituted pyrroles by reaction of Nvinylic phosphazenes derived from β-amino acids with α-bromo ketones is described.