cas 28232-66-8, 3-Bromo-5-(4-chlorophenoxy)pyridine | Articles data ｜lookchem

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28232-66-8

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Structure-activity studies of 7-heteroaryl-3-azabicyclo[3.3.1]non-6-enes: A novel class of highly potent nicotinic receptor ligands
The potential for nicotinic ligands with affinity for the α4β2 or α7 subtypes to treat such diverse diseases as nicotine addiction, neuropathic pain, and neurodegenerative and cognitive disorders has been exhibited clinically for several compounds while p
Breining, Scott R.,Melvin, Matt,Bhatti, Balwinder S.,Byrd, Gary D.,Kiser, Melanie N.,Hepler, Christopher D.,Hooker, Dawn N.,Zhang, Jenny,Reynolds, Leslie A.,Benson, Lisa R.,Fedorov, Nikolai B.,Sidach, Serguei S.,Mitchener, J. Pike,Lucero, Linda M.,Lukas, Ronald J.,Whiteaker, Paul,Yohannes, Daniel
p. 9929 - 9945
(2013/01/16)

Synthesis of novel halo-oxybispyridines, new building blocks in cholinergic medicinal chemistry
This paper describes a method for the preparation of oxybispyridines bearing several halogens, which could be further transformed into other functional groups thus giving access to libraries with the bis-pyridyl ether moiety as the common structural feature of interest in cholinergic medicinal chemistry. Scope and limitation of the method are outlined.
Voisin, Anne Sophie,Bouillon, Alexandre,Lancelot, Jean-Charles,Lesnard, Aurélien,Rault, Sylvain
p. 6000 - 6005
(2007/10/03)

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Chemical Properties

Melting Point: 79 °C
Boiling Point: 341.402 °C at 760 mmHg
Flash Point:160.274 °C
Density: 1.569 g/cm³
Storage Temp.:2-8°C
Refractive Index: 1.616
PSA: 22.12000
LogP: 4.28980

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