28401-39-0Relevant articles and documents
ENZYMATIC KINETIC RESOLUTION OF CYANOHYDRIN ACETATES AND ITS APPLICATION TO THE SYNTHESIS OF (S)-(-)-FRONTALIN
Ohta, Hiromichi,Kimura, Yoichi,Sugano, Yasushi,Sugai, Takeshi
, p. 5469 - 5476 (2007/10/02)
Kinetic resolution of racemic 1-cyano-1-methylalkyl and alkenyl acetates has been achieved on incubation with Pichia miso IAM 4682, which hydrolyzed selectively the (R)-enantiomer, leving behind the (S)-enantiomer intact.The chiral 1-cyano-1-methyl-5-hexenyl acetate thus obtained was converted to (S)-frontalin via unsaturated diol.
SYNTHESIS OF THE PHEROMONES, (E)-3,7-DIMETHYL-2,7-OCTADIENYL PROPIONATE, (E)-3,7-DIMETHYL-2-OCTENE-1,8-DIOL AND FRONTALIN FROM A COMMON INTERMEDIATE
Dhokte, U. P.,Rao, A. S.
, p. 811 - 822 (2007/10/02)
Ketal ester 9 has been prepared in five steps from methyl levulinate 4 (scheme 1).The propionate 1, diol 2 and (+/-) frontalin 3 were prepared from ester 9 employing the routes shown in scheme 2,3 and 4 respectively.The branched chain alkenes 13 and 20 were prepared conveniently from the primary alcohols 11 and 10 following the procedure of S.Wolff.Triethyl phosphonopropionate 7 has been prepared by methylating triethylphosphonoacetate with methyl iodide in the presence of sodium hydride.
CONVENIENT SYNTHETIC ROUTE TO (+/-) -FRONTALIN
Kongkathip, Boonsong,Sokkho, Rongsan,Kongkathip, Ngampong
, p. 1849 - 1850 (2007/10/02)
(+/-)-Frontalin was synthesized in a few steps sequence starting from ethyl acetoacetate involving intramolecular cyclization using palladium chloride as catalyst