28537-72-6

Basic information

• Product Name: 1,7-BIS(MALEIMIDE)HEPTANE
• Synonyms: 1,7-BIS(MALEIMIDE)HEPTANE;1,1'-(1,7-Heptanediyl)bis(1H-pyrrole-2,5-dione);N,N'-(1,7-Heptanediyl)di(maleimide)
• CAS NO: 28537-72-6
• Molecular Formula: C15H18N2O4
• Molecular Weight: 290.31
• Product Categories: pharmacetical
• Mol File: 28537-72-6.mol

Chemical Properties

• Boiling Point: 474.6°Cat760mmHg
• Flash Point: 218.4°C
• Appearance: /
• Density: 1.271g/cm³
• CAS DataBase Reference: 1,7-BIS(MALEIMIDE)HEPTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,7-BIS(MALEIMIDE)HEPTANE(28537-72-6)
• EPA Substance Registry System: 1,7-BIS(MALEIMIDE)HEPTANE(28537-72-6)

Safety Data

• Hazardous Substances Data: 28537-72-6(Hazardous Substances Data)

Usage

Chemical compound

1,7-Bis(maleimide)heptane is a chemical compound that is widely used in the field of materials science and polymer chemistry.

Reactive diene

It is a reactive diene, which means it can react with other compounds to form new chemical bonds.

Crosslinking agent

1,7-Bis(maleimide)heptane is often employed as a crosslinking agent in the production of polymers and resins. This means it can be used to connect different polymer chains, creating a network structure.

Reactivity with thiols

Its maleimide groups are highly reactive towards thiols, which are compounds that contain a sulfur-hydrogen bond. This makes it a valuable component in the synthesis of bioconjugates and protein modifications.

Synthesis of bioconjugates and protein modifications

1,7-Bis(maleimide)heptane is often used in the synthesis of bioconjugates, which are molecules that are formed by the covalent attachment of two or more different biological molecules, and in the modification of proteins, which are large, complex molecules that play many critical roles in the body.

Development of functionalized materials

1,7-Bis(maleimide)heptane is often utilized in the development of functionalized materials, such as hydrogels and nanocomposites. These are materials that have been modified to have specific properties or functions.

Ability to form covalent bonds

1,7-Bis(maleimide)heptane has the ability to form covalent bonds with a variety of substrates, which are substances that are acted upon by an enzyme or subject to a chemical reaction.

Unique structure and reactivity

Its unique structure and reactivity make it a versatile and important compound in various fields of chemical research and industrial applications. This means that it can be used in a wide range of different applications and can be modified in different ways to achieve different results.

Upstream product

• 4549-31-9 1,7-dibromoheptane 
• 1449656-03-4 C₂₃H₂₆N₂O₆ 

Relevant articles and documents

An efficient reverse Diels-Alder approach for the synthesis of N-alkyl bismaleimides

Bismaleimides are useful precursors for Diels-Alder reactions, Michael additions, and thiol-maleimide based conjugation for the synthesis of materials and polymers. Use of bismaleimide cross linkers for generating polymers, bioconjugate molecules, and useful imaging molecules is an active area of research. An efficient and practical synthetic protocol for N-alkyl bis-maleimide cross linkers starting from furan protected maleimide employing a reverse Diels-Alder reaction is reported.