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2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one is a chemical compound characterized by its unique structural formula, featuring a pyrano[2,3-b]pyridin-4(4H)-one ring system. It is recognized for its potential as a building block in the development of new drug candidates, particularly for neurological and neurodegenerative disorders.

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  • 286472-03-5 Structure
  • Basic information

    1. Product Name: 2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one
    2. Synonyms: 2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one;2H-thiopyrano[2,3-b]pyridin-4(3H)-one;2,3-dihydrothiopyrano[2,3-b]pyridin-4-one
    3. CAS NO:286472-03-5
    4. Molecular Formula: C8H7NOS
    5. Molecular Weight: 149.14668
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 286472-03-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 326.6±31.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.316±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 1.08±0.20(Predicted)
    10. CAS DataBase Reference: 2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one(286472-03-5)
    12. EPA Substance Registry System: 2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one(286472-03-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 286472-03-5(Hazardous Substances Data)

286472-03-5 Usage

Uses

Used in Pharmaceutical Industry:
2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one is used as an intermediate in the synthesis of pharmaceuticals for its versatile reactivity and functional group compatibility, which makes it an attractive target for chemical modification and derivatization in drug discovery and development processes.
Used in Agrochemical Industry:
2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one is also utilized as an intermediate in the synthesis of agrochemicals, contributing to the development of new compounds for agricultural applications.
Ongoing research is focused on exploring the potential applications of 2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one and its derivatives further, with the aim of expanding their use in the pharmaceutical industry and potentially other sectors.

Check Digit Verification of cas no

The CAS Registry Mumber 286472-03-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,6,4,7 and 2 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 286472-03:
(8*2)+(7*8)+(6*6)+(5*4)+(4*7)+(3*2)+(2*0)+(1*3)=165
165 % 10 = 5
So 286472-03-5 is a valid CAS Registry Number.

286472-03-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-Dihydropyrano[2,3-b]pyridin-4(4H)-one

1.2 Other means of identification

Product number -
Other names 4-Nitro-indan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:286472-03-5 SDS

286472-03-5Relevant articles and documents

Synthesis of novel 5H,11H-pyrido[2',3':2,3]thiopyrano[4,3-b]-indoles by Fischer-indole cyclization

Da Settimo, Antonio,Marini, Anna Maria,Primofiore, Giampaolo,Da Settimo, Federico,Salerno, Silvia,La Motta, Concettina,Pardi, Gianluca,Ferrarini, Pier Luigi,Mori, Claudio

, p. 379 - 382 (2000)

The synthesis of the title compounds 5H,11H- pyrido[2',3':2,3]thiopyrano[4,3-b]indoles was accomplished by the Fischer indole cyclization of some 2,3-dihydrothiopyrano[2,3-b]pyridin-4(4H)-one phenylhydrazones and 7-methyl-2,3-dihydrothiopyrano[2,3-b]pyrid

Tricyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors

-

Page/Page column 24, (2010/11/25)

This invention relates to certain tricyclic 6-alkylidene penems which act as a inhibitor of class-D enzymes. β-Lactamases hydrolyze β-lactam antibiotics, and as such serve as the primary cause of bacterial resistance. The compounds of the present inventio

HETEROTRICYCLYL 6-ALKYLIDENE-PENEMS AS ΒΕΤΑ-LACTAMASE INHIBITORS

-

Page/Page column 136, (2008/06/13)

The present invention provides a compound of formula I, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.

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