286472-03-5Relevant articles and documents
Synthesis of novel 5H,11H-pyrido[2',3':2,3]thiopyrano[4,3-b]-indoles by Fischer-indole cyclization
Da Settimo, Antonio,Marini, Anna Maria,Primofiore, Giampaolo,Da Settimo, Federico,Salerno, Silvia,La Motta, Concettina,Pardi, Gianluca,Ferrarini, Pier Luigi,Mori, Claudio
, p. 379 - 382 (2000)
The synthesis of the title compounds 5H,11H- pyrido[2',3':2,3]thiopyrano[4,3-b]indoles was accomplished by the Fischer indole cyclization of some 2,3-dihydrothiopyrano[2,3-b]pyridin-4(4H)-one phenylhydrazones and 7-methyl-2,3-dihydrothiopyrano[2,3-b]pyrid
Tricyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors
-
Page/Page column 24, (2010/11/25)
This invention relates to certain tricyclic 6-alkylidene penems which act as a inhibitor of class-D enzymes. β-Lactamases hydrolyze β-lactam antibiotics, and as such serve as the primary cause of bacterial resistance. The compounds of the present inventio
HETEROTRICYCLYL 6-ALKYLIDENE-PENEMS AS ΒΕΤΑ-LACTAMASE INHIBITORS
-
Page/Page column 136, (2008/06/13)
The present invention provides a compound of formula I, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof.