cas 28694-94-2, Methyl 2-(4-aMino-3-nitrophenyl)acetate | Articles data ｜lookchem

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28694-94-2

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N-{[2-(PIPERIDIN-1-YL)PHENYL](PHENYL)METHYL}-2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXA ZIN-7-YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ROR-GAMMA MODULATORS FOR TREATING AUTOIMMUNE DISEASES
The present invention provides e.g. N-{[2-(piperidin-1-yl)phenyl] (phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating e.g. autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases or cholestatic diseases, such as e.g. arthitis and asthma.
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Page/Page column 68; 69; 70

(2018/08/20)

COMPOUNDS AND METHODS
The present invention relates to novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORy.
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Page/Page column 115

(2013/03/26)

HETEROCYCLIC KINASE INHIBITORS
Compounds having the formula (I) are useful for inhibiting protein kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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Page 57 - 58

(2010/02/08)

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Chemical Properties

Boiling Point: 371.7±27.0 °C(Predicted)
Density: 1.344±0.06 g/cm3(Predicted)
PKA: -0.33±0.45(Predicted)
PSA: 98.14000
LogP: 1.99690

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