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1,2-Bis[2'-(trifluoromethyl)phenyl]ethane is a chemical compound with a unique molecular structure, featuring an ethane core to which two phenyl groups are attached. These phenyl groups are substituted with trifluoromethyl groups, which are known for their electron-withdrawing properties. This characteristic can influence the compound's reactivity and other properties, making it a subject of interest in scientific research and study.

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  • 287172-66-1 Structure
  • Basic information

    1. Product Name: 1,2-BIS[2'-(TRIFLUOROMETHYL)PHENYL]ETHANE
    2. Synonyms: 1.2-BIS(2-TRIFLUOROMETHYLPHENYL)ETHAN;1,2-BIS-(2-TRIFLUOROMETHYLPHENYL)ETHANE;1,2-BIS[2'-(TRIFLUOROMETHYL)PHENYL]ETHANE;[2,2'-BIS(TRIFLUOROMETHYL)DIBENZYL];1,2-Bis[2'-(trifluoromethyl)phenyl]ethane97%;1,1'-Ethane-1,2-diylbis[2-(trifluoromethyl)benzene] 97%;1,1'-Ethane-1,2-diylbis[2-(trifluoromethyl)benzene]97%
    3. CAS NO:287172-66-1
    4. Molecular Formula: C16H12F6
    5. Molecular Weight: 318.26
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 287172-66-1.mol
  • Chemical Properties

    1. Melting Point: 74-75°C
    2. Boiling Point: 270.7°Cat760mmHg
    3. Flash Point: 92.1°C
    4. Appearance: /
    5. Density: 1.273g/cm3
    6. Vapor Pressure: 0.0112mmHg at 25°C
    7. Refractive Index: 1.473
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 1,2-BIS[2'-(TRIFLUOROMETHYL)PHENYL]ETHANE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1,2-BIS[2'-(TRIFLUOROMETHYL)PHENYL]ETHANE(287172-66-1)
    12. EPA Substance Registry System: 1,2-BIS[2'-(TRIFLUOROMETHYL)PHENYL]ETHANE(287172-66-1)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 287172-66-1(Hazardous Substances Data)

287172-66-1 Usage

Uses

Due to the limited information available in the public domain, the specific applications of 1,2-Bis[2'-(trifluoromethyl)phenyl]ethane are not well-documented. However, given its unique molecular structure and properties, it is likely used in various scientific research and study applications. The electron-withdrawing nature of the trifluoromethyl groups may make it a candidate for use in:
Used in Chemical Research:
1,2-Bis[2'-(trifluoromethyl)phenyl]ethane is used as a research compound for studying its reactivity and properties due to the presence of electron-withdrawing trifluoromethyl groups.
Used in Pharmaceutical Development:
1,2-Bis[2'-(trifluoromethyl)phenyl]ethane may be used as a starting material or intermediate in the synthesis of pharmaceutical compounds, given its unique molecular structure and potential reactivity.
Used in Material Science:
1,2-BIS[2'-(TRIFLUOROMETHYL)PHENYL]ETHANE could be employed in the development of new materials with specific properties, such as improved stability or reactivity, due to the influence of the trifluoromethyl groups on its molecular structure.

Check Digit Verification of cas no

The CAS Registry Mumber 287172-66-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,7,1,7 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 287172-66:
(8*2)+(7*8)+(6*7)+(5*1)+(4*7)+(3*2)+(2*6)+(1*6)=171
171 % 10 = 1
So 287172-66-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H12F6/c17-15(18,19)13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)16(20,21)22/h1-8H,9-10H2

287172-66-1 Well-known Company Product Price

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  • Alfa Aesar

  • (B24533)  1,2-Bis[2-(trifluoromethyl)phenyl]ethane, 97%   

  • 287172-66-1

  • 1g

  • 190.0CNY

  • Detail
  • Alfa Aesar

  • (B24533)  1,2-Bis[2-(trifluoromethyl)phenyl]ethane, 97%   

  • 287172-66-1

  • 5g

  • 711.0CNY

  • Detail

287172-66-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(trifluoromethyl)-2-[2-[2-(trifluoromethyl)phenyl]ethyl]benzene

1.2 Other means of identification

Product number -
Other names 1,2-Bis[2'-(trifluoromethyl)phenyl]ethane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:287172-66-1 SDS

287172-66-1Downstream Products

287172-66-1Relevant articles and documents

Formation of quaternary carbons through cobalt-catalyzed C(sp3)-C(sp3) Negishi cross-coupling

Palao, Eduardo,López, Enol,Torres-Moya, Iván,De La Hoz, Antonio,Díaz-Ortiz, ángel,Alcázar, Jesús

supporting information, p. 8210 - 8213 (2020/08/17)

Formation of all-carbon-substituted quaternary carbons is a key challenge in organic and medicinal chemistry. We report a cobalt-catalyzed C(sp3)-C(sp3) cross-coupling that allows for the introduction of benzyl, heteroarylmethylzinc and allyl groups to halo-carbonyl substrates. The cross-coupling reaction is selective for C(sp3)-over C(sp2)-halides, in contrast to most used catalytic metals, and allows access to novel scaffolds of pharmaceutical interest. NMR mechanistic studies suggest the presence of Co(0) complexes as catalytic species. This journal is

Photochemical Reductive C–C Coupling with a Guanidine Electron Donor

Wiesner, Sven,Walter, Petra,Wagner, Arne,Kaifer, Elisabeth,Himmel, Hans-J?rg

, p. 5045 - 5054 (2016/10/26)

The metal-free photoinduced reductive C–C coupling reactions of a number of substituted benzyl halides (15 examples) with the organic electron-donor 2,3,5,6-tetrakis(tetramethylguanidino)pyridine are evaluated. Depending on the substituents at the benzyl group, a C–C coupling product yield in the range 50–95 % is achieved. The photochemical benzyl-radical formation by homolytic N–C bond cleavage of the initially formed benzyl-pyridinium salts is the rate-determining step of these reactions. Electron-withdrawing as well as -donating substituents at the phenyl group increase the reaction rate. Quantum chemical computations did not reveal any correlation between either the enthalpy or Gibbs free energy of the N–C bond cleavage step and the experimentally determined first-order rate constants. Instead, the structural difference between the excited state generated by irradiation and the electronic ground state of the pyridinium ions could be used to rationalize the differences in the reaction rates.

IRON BISPHENOLATE COMPLEXES AND METHODS OF USE AND SYNTHESIS THEREOF

-

Paragraph 00282; 00283; 00286, (2013/04/25)

The present application, relates to iron bisphenolate complexes and methods of use and synthesis thereof. The iron complexes are prepared from tridentate or tetradentate ligands of Formula I: wherein R1 and R2 are as defined herein. Also provided are methods and processes of using the iron bisphenolate complexes as catalysts in cross-coupling reactions and in controlled radical polymerizations.

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