287194-30-3

Basic information

• Product Name: 2-(2,5-diMethoxyphenylcarbaMoyl)phenyl acetate
• Synonyms: 2-(2,5-diMethoxyphenylcarbaMoyl)phenyl acetate;Benzamide, 2-(acetyloxy)-N-(2,5-dimethoxyphenyl)-
• CAS NO: 287194-30-3
• Molecular Formula: C₁₇H₁₇NO₅
• Molecular Weight: 315.32058
• Mol File: 287194-30-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2,5-diMethoxyphenylcarbaMoyl)phenyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,5-diMethoxyphenylcarbaMoyl)phenyl acetate(287194-30-3)
• EPA Substance Registry System: 2-(2,5-diMethoxyphenylcarbaMoyl)phenyl acetate(287194-30-3)

Safety Data

• Hazardous Substances Data: 287194-30-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
2-(2,5-dimethoxyphenylcarbamoyl)phenyl acetate is used as a building block for the synthesis of novel compounds in pharmaceutical research and drug development. Its unique structure and reactivity allow for the creation of new molecules with potential therapeutic applications.
Used in Organic Synthesis and Chemical Reactions:
In the laboratory, 2-(2,5-dimethoxyphenylcarbamoyl)phenyl acetate is used as a valuable tool in organic synthesis and chemical reactions. Its distinctive structure and reactivity facilitate the development of new synthetic pathways and the exploration of chemical properties.
Used in Drug Discovery and Development:
2-(2,5-dimethoxyphenylcarbamoyl)phenyl acetate is employed in drug discovery and development due to its potential biological activities and medicinal properties. Its exploration in this field may lead to the identification of new therapeutic agents with various applications in medicine.
Used in Chemical Industry:
2-(2,5-dimethoxyphenylcarbamoyl)phenyl acetate is utilized in the chemical industry for the synthesis of various chemical products. Its unique structure and functional groups make it a versatile component in the production of specialty chemicals and intermediates for further chemical transformations.

Upstream product

• 102-56-7 2,5-dimethoxyaniline 
• 5538-51-2 O-acetylsalicyloyl chloride 

Downstream Products

• 287194-31-4 acetic acid 2-(6,6-dimethoxy-3-oxocyclohexa-1,4-dienylcarbamoyl)phenyl ester 
• 287194-37-0 N-(2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2-hydroxybenzamide 
• 326499-50-7 3,3-dimethoxy-4,5-epoxy-6-hydroxy-2-salicyloylamino-cyclohexene 
• 287194-40-5 (-)-2-hydroxy-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)benzamide 
• 287194-41-6 2-hydroxy-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)benzamide 

Relevant articles and documents

Preparation and biological activities of optically active dehydroxymethylepoxyquinomicin, a novel NF-κB inhibitor

NF-κB is a transcription factor that induces inflammatory cytokines and anti-apoptotic proteins. We have designed a new NF-κB inhibitor based on the structure of the antibiotic epoxyquinomicin C. The designed compound, dehydroxymethylepoxyquinomicin (DHME

Salicylamide derivatives

Salicylamide derivatives represented by formulae (1a) and (1b); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active ingredient. The salicylamide derivatives represented by formulae (1a) an

Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin C

In order to develop new inhibitors of NF-κB activation, we designed and synthesized dehydroxymethyl derivatives of epoxyquinomicin C, namely, DHM2EQ and its regioisomer DHM3EQ. These derivatives were synthesized from 2,5-dimethoxyaniline in 5 steps. Since DHM2EQ was more active and less toxic than DHM3EQ, its stereochemical configuration was determined by X-ray crystallographic analysis. Each enantiomer of the protected DHM2EQ was separated by a chiral column and deprotected. DHM2EQ inhibited TNF-α-induced activation of NF-κB in human T cell leukemia cells, and also inhibited collagen-induced arthritis in a rheumatoid model in mice. (C) 2000 Elsevier Science Ltd. All rights reserved.