287966-62-5

Basic information

• Product Name: DESULFOGLUCORAPHANIN
• Synonyms: DESULFOGLUCORAPHANIN;1-Thio-1-[N-hydroxy-5-(Methylsulfinyl)pentaniMidate] β-D-Glucopyranose;4-Methylsulfinylbutyldesulfoglucosinolate
• CAS NO: 287966-62-5
• Molecular Formula: C12H23NO7S2
• Molecular Weight: 357.446
• Product Categories: Aliphatics;Carbohydrates & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Aliphatics, Carbohydrates & Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 287966-62-5.mol

Chemical Properties

• Boiling Point: 706.0±70.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: Methanol, Water
• PKA: 10.97±0.10(Predicted)
• CAS DataBase Reference: DESULFOGLUCORAPHANIN(CAS DataBase Reference)
• NIST Chemistry Reference: DESULFOGLUCORAPHANIN(287966-62-5)
• EPA Substance Registry System: DESULFOGLUCORAPHANIN(287966-62-5)

Safety Data

• Hazardous Substances Data: 287966-62-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
DESULFOGLUCORAPHANIN is used as a pharmaceutical candidate for its potential health benefits. It is being studied for its potential role in cancer prevention and treatment due to its ability to modulate various biological pathways and exhibit anticancer properties.
Used in Food Industry:
DESULFOGLUCORAPHANIN is used as a natural food additive for its potential health-promoting properties. It can be incorporated into food products derived from cruciferous vegetables, contributing to their overall nutritional value and health benefits.
Used in Cosmetic Industry:
DESULFOGLUCORAPHANIN can be used as an ingredient in cosmetic products for its potential antioxidant and anti-inflammatory properties. It may help protect the skin from environmental stressors and promote a healthy complexion.
Used in Agricultural Industry:
DESULFOGLUCORAPHANIN can be used in agricultural applications to enhance the nutritional content and health benefits of cruciferous vegetables. It may also be used as a natural pesticide or growth promoter to improve crop yield and quality.

Relevant articles and documents

Rapid and Efficient Desulfonation Method for the Analysis of Glucosinolates by High-Resolution Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry

The goal of our present research was to develop a simple and rapid method for the quantitation of desulfoglucosinolates (desulfoGLS) without using column chromatography. The proposed method involves extraction, concentration, incubation of glucosinolates with a sulfatase enzyme, and HPLC analysis. Identification of desulfoGLS in green kohlrabi was performed by LC-HR-ESI-QTOF-MS in positive-ionization mode. A total of 11 desulfoGLS were identified with neoglucobrassicin (3.32 ± 0.05 μmol/g DW) as the predominant indolyl, whereas progoitrin and sinigrin were the major aliphatic desulfoGLS. The levels of the aliphatic desulfoGLS glucoiberin, progoitrin, and glucoerucin at 7 h were found to be 3.6-, 1.9-, and 1.6-fold higher, respectively, than those produced through the conventional method. This technique was successfully applied in the identification of desulfoGLS from cabbage. The developed method has fewer unit operations, has maximum recovery, and is reproducible in the determination of desulfoGLS in a large number of Brassicaceae samples in a short time.

Benzoic acid glucosinolate esters and other glucosinolates from Arabidopsis thaliana.

The spectacular recent progress in Arabidopsis thaliana molecular genetics furnishes outstanding tools for studying the formation and function of all metabolites in this cruciferous species. One of the major groups of secondary metabolites in A. thaliana is the glucosinolates. These hydrophilic, sulfur-rich glycosides appear to serve as defenses against some generalist herbivores and pathogens, and as feeding and oviposition stimulants to specialist herbivores. To help study their biosynthesis and role in plant-insect interactions, we wanted to determine the complete glucosinolate content of A. thaliana. In previous studies, 24 glucosinolates had been identified from ecotype Columbia. We reinvestigated Columbia as well as additional ecotypes and mutant lines, and identified 12 further glucosinolates, including five novel compounds. Structures were elucidated by MS and NMR spectroscopy of their desulfated derivatives, and by enzymatic cleavage of the attached ester moieties. Four of the novel glucosinolates are benzoate esters isolated from the seeds. In all but one of these compounds, esterification is on the glucose moiety rather than the side chain, a very unusual feature for glucosinolates. Among additional glucosinolates identified were the first non-chain elongated, methionine-derived glucosinolate from A. thaliana and the first compounds that appear to be derived from leucine.