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4-Amino-1-Boc-piperidine-4-carboxamide is a complex organic compound that belongs to the class of organic compounds known as piperidines. The 'Boc' in its name refers to tert-butyloxycarbonyl, a protective group used in organic synthesis. It plays a significant role in the field of medicinal chemistry due to its usage as an intermediate in the synthesis of various drugs. Like other piperidines, it is expected to have a basic nature due to the presence of nitrogen in the piperidine ring.

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  • 288154-18-7 Structure
  • Basic information

    1. Product Name: 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXAMIDE
    2. Synonyms: 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXAMIDE;tert-Butyl 4-amino-4-carbamoylpiperidine-1-carboxylate;1-Boc-4-aMinopiperidine-4-carboxaMide
    3. CAS NO:288154-18-7
    4. Molecular Formula: C11H21N3O3
    5. Molecular Weight: 243.3
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 288154-18-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXAMIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXAMIDE(288154-18-7)
    11. EPA Substance Registry System: 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXAMIDE(288154-18-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 288154-18-7(Hazardous Substances Data)

288154-18-7 Usage

Uses

Used in Pharmaceutical Industry:
4-Amino-1-Boc-piperidine-4-carboxamide is used as a synthetic intermediate for the production of pharmaceutical drugs. Its role in the synthesis process is crucial for creating a variety of bioactive compounds that can be used for medicinal purposes.
Used in Research and Development:
4-Amino-1-Boc-piperidine-4-carboxamide is used as a research chemical, allowing scientists to explore its properties and potential applications in the development of new drugs and therapeutic agents. This helps in advancing the understanding of medicinal chemistry and contributes to the discovery of novel treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 288154-18-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,8,1,5 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 288154-18:
(8*2)+(7*8)+(6*8)+(5*1)+(4*5)+(3*4)+(2*1)+(1*8)=167
167 % 10 = 7
So 288154-18-7 is a valid CAS Registry Number.

288154-18-7 Well-known Company Product Price

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  • Aldrich

  • (JWP00025)  4-Amino-1-Boc-piperidine-4-carboxamide  AldrichCPR

  • 288154-18-7

  • JWP00025-1G

  • 2,901.60CNY

  • Detail

288154-18-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 4-amino-4-carbamoylpiperidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names tert-butyl 4-amino-4-(aminocarbonyl)piperidine-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:288154-18-7 SDS

288154-18-7Relevant articles and documents

Spiro compound

-

, (2020/07/06)

The invention discloses a spiro compound, application thereof and a pharmaceutical composition containing the spiro compound. The structure of the compound is shown as a formula I, and the compound has a good inhibition effect on RET kinase.

RET inhibitor

-

, (2020/06/20)

The invention discloses a compound, application thereof and a pharmaceutical composition containing the compound. The structure of the compound is shown as a formula I, and the compound has a good inhibition effect on RET kinase.

SUBSTITUTED HETEROCYCLIC INHIBITORS OF PTPN11

-

Page/Page column 0341-0342, (2019/11/19)

The present invention relates to compounds which may be useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their applica

HETEROCYCLIC INHIBITORS OF PTPN11

-

Paragraph 0442; 0443, (2018/01/04)

The present invention relates to compounds which may be useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their applica

ACETYL CoA CARBOXYLASE INHIBITORS

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Page/Page column 51, (2009/10/17)

The present invention relates to acetyl coenzyme-A carboxylase (""ACC"") inhibiting compounds of the formula wherein the variables are as defined herein. In particular, the present invention relates to ACC1 and/or ACC2 inhibitors, compositions of matter,

CGRP RECEPTOR ANTAGONISTS

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Page/Page column 61, (2010/11/08)

The present invention is directed to compounds of Formula I: Formula I: I and Formula II: (where variables R1, R2, R3, R4, A, B, J, Q, T, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

CGRP RECEPTOR ANTAGONISTS

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Page/Page column 98, (2010/11/08)

Compounds of Formula (I): and Formula (II): (where variables R2, R4, A, B, D, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

A rational approach to the design and synthesis of a new bradykinin B1 receptor antagonist

Bedos, Philippe,Amblard, Muriel,Subra, Gilles,Dodey, Pierre,Luccarini, Jean-Michel,Paquet, Jean-Luc,Pruneau, Didier,Aumelas, André,Martinez, Jean

, p. 2387 - 2394 (2007/10/03)

We have previously synthesized a potent and selective B1 bradykinin receptor antagonist, JMV1645 (H-Lys-Arg-Pro-Hyp-Gly-Igl-Ser-D-BT-OH), containing a dipeptide mimetic ((3S)-amino-5-carbonylmethyl-2,3-dihydro-1,5- benzothiazepin-4(5H)-one (D-B

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