Bis acyl phosphine oxide compound and polymerizable composition containing the same
PROBLEM TO BE SOLVED: To provide a new acylphosphine oxide compound which can impart high dentin adhesiveness to a composition, when combined with a polymerizable monomer to form the composition, and can impart stable adhesiveness little in irregularity a
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Paragraph 0142; 0146
(2016/12/16)
USE OF ESTROGEN DERIVATIVES FOR THE MANUFACTURE OF PHARMACEUTICAL PRODUCTS USEFUL FOR THE PROPHYLAXIS AND/OR TREATMENT OF PSYCHIATRIC DISEASES
The object of the invention is the use of the derivatives of 17-alpha-estradiol of formula (I) where R means ? ethyl, higher alkyl, cycloalkyl, aryl and heterocycle as well as hydroxyl, alkyl groups containing amino and carboxy groups; or ? CO-O-R', where
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Page/Page column 12; 13
(2013/07/19)
Rapamycin Carbonic Ester Analogues, Pharmaceutical Compositions, Preparations and Uses Thereof
Rapalogs of formula I, pharmaceutically acceptable salts, pharmaceutical compositions, and preparation methods and uses thereof. The rapalogs have the structure of formula I and can be used as an anti-tumor medicament. Comparing with rapamycin, the rapalogs of the present invention exhibit enhanced water solubility, and improved pharmacological and pharmacokinetic properties by introducing a hydrophilic and polar group such as a hydroxyl.
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Page/Page column 8-9
(2011/07/29)
RAPAMYCIN CARBONIC ESTER ANALOGUES, PHARMACEUTICAL COMPOSITIONS, PREPARATIONS AND USES THEREOF
Rapalogs of formula I, pharmaceutically acceptable salts, pharmaceutical compositions, and preparation methods and uses thereof. The rapalogs have the structure of formula I and can be used as an anti-tumor medicament. Comparing with rapamycin, the rapalogs of the present invention exhibit enhanced water solubility, and improved pharmacological and pharmacokinetic properties by introducing a hydrophilic and polar group such as a hydroxyl.
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Page/Page column 12
(2011/08/08)
Milbemycin 5-carbonate derivatives and compositions containing them
5-Carbonate derivatives of milbemycins A3, A4 and A5 have valuable acaricidal, anthelmintic and other activities, especially against endo- and exoparasites.
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(2008/06/13)
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