2901-66-8Relevant articles and documents
CHEMOTHERAPEUTIC FOR INDUCING AN MSH2-DEPENDENT APOPTOTIC PATHWAY
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Page/Page column 18, (2009/04/25)
A method of treating cancer in a subject in need thereof comprises administering said subject reserpine, yohimbine, an analog thereof, or a pharmaceutically acceptable salt or prodrug thereof, in an amount effective to treat the cancer. Compounds and compositions useful for carrying out the method are also described.
Process for the Semisynthesis of Deserpidine
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Page/Page column 3, (2008/12/07)
The present invention relates to an efficient procedure for the synthesis of deserpidine (Ia), starting from reserpic acid lactone (II) via the intermediate 11-O-demethyl reserpic acid lactone (III).
Regiospecific and stereoselective syntheses of (±)-reserpine and (-)-reserpine
Stork, Gilbert,Tang, Peng Cho,Casey, Michael,Goodman, Burton,Toyota, Masahiro
, p. 16255 - 16262 (2007/10/03)
Full details of three approaches to an entirely regio- and Stereoselective synthesis of the well-known target reserpine are described, culminating in a total synthesis which efficiently meets these requirements.
A PROCESS FOR THE SEMISYNTHESIS OF DESERPIDINE
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Page/Page column 6, (2010/02/14)
The present invention relates to an efficient procedure for the synthesis of deserpidine (Ia), starting from reserpic acid lactone (II) via the intermediate 11-O-demethyl reserpic acid lactone (III).
Total synthesis of (-)-reserpine using the chiron approach
Hanessian, Stephen,Pan, Jingwen,Carnell, Andrew,Bouchard, Herve,Lesage, Luc
, p. 465 - 473 (2007/10/03)
A highly stereocontrolled synthesis of ring D/E precursor to reserpine has been developed starting from (-)-quinic acid as a chiral template. The total synthesis of (-)-reserpine is described through the cyclization of an immonium lactam intermediate.