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methyl (3beta,16beta,17alpha,18beta,20alpha)-18-hydroxy-11,17-dimethoxyyohimban-16-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • Yohimban-16-carboxylicacid, 18-hydroxy-11,17-dimethoxy-, methyl ester, (3b,16b,17a,18b,20a)-

    Cas No: 2901-66-8

  • USD $ 1.9-2.9 / Gram

  • 100 Gram

  • 1000 Metric Ton/Month

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  • 2901-66-8 Structure
  • Basic information

    1. Product Name: methyl (3beta,16beta,17alpha,18beta,20alpha)-18-hydroxy-11,17-dimethoxyyohimban-16-carboxylate
    2. Synonyms: methyl (3beta,16beta,17alpha,18beta,20alpha)-18-hydroxy-11,17-dimethoxyyohimban-16-carboxylate;(3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-hydroxyyohimban-16-carboxylic acid methyl ester;(3β,20α)-18β-Hydroxy-11,17α-dimethoxyyohimban-16β-carboxylic acid methyl ester;Reserpic acid methyl;(3β,16β,17α,18β,20α)-18-Hydroxy-11,17-diMethoxy-yohiMban-16-carboxylic Acid Methyl Ester;Methyl reserpinolate;NSC 81464;Reserpic Acid Methyl Ester
    3. CAS NO:2901-66-8
    4. Molecular Formula: C23H30N2O5
    5. Molecular Weight: 414.4947
    6. EINECS: 220-792-3
    7. Product Categories: N/A
    8. Mol File: 2901-66-8.mol
  • Chemical Properties

    1. Melting Point: 244.5°C
    2. Boiling Point: 533.37°C (rough estimate)
    3. Flash Point: 309.3°C
    4. Appearance: /
    5. Density: 1.2138 (rough estimate)
    6. Vapor Pressure: 1.17E-14mmHg at 25°C
    7. Refractive Index: 1.6300 (estimate)
    8. Storage Temp.: Refrigerator
    9. Solubility: Chloroform (Slightly), Dichloromethane, Dimethyl Sulfoxide, Methanol (Slightly)
    10. PKA: 14.03±0.60(Predicted)
    11. CAS DataBase Reference: methyl (3beta,16beta,17alpha,18beta,20alpha)-18-hydroxy-11,17-dimethoxyyohimban-16-carboxylate(CAS DataBase Reference)
    12. NIST Chemistry Reference: methyl (3beta,16beta,17alpha,18beta,20alpha)-18-hydroxy-11,17-dimethoxyyohimban-16-carboxylate(2901-66-8)
    13. EPA Substance Registry System: methyl (3beta,16beta,17alpha,18beta,20alpha)-18-hydroxy-11,17-dimethoxyyohimban-16-carboxylate(2901-66-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. RIDADR: 1544
    5. WGK Germany:
    6. RTECS:
    7. HazardClass: 6.1(b)
    8. PackingGroup: III
    9. Hazardous Substances Data: 2901-66-8(Hazardous Substances Data)

2901-66-8 Usage

Chemical Properties

Light Yellow Solid

Check Digit Verification of cas no

The CAS Registry Mumber 2901-66-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,0 and 1 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2901-66:
(6*2)+(5*9)+(4*0)+(3*1)+(2*6)+(1*6)=78
78 % 10 = 8
So 2901-66-8 is a valid CAS Registry Number.
InChI:InChI=1/C23H30N2O5/c1-28-13-4-5-14-15-6-7-25-11-12-8-19(26)22(29-2)20(23(27)30-3)16(12)10-18(25)21(15)24-17(14)9-13/h4-5,9,12,16,18-20,22,24,26H,6-8,10-11H2,1-3H3

2901-66-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Reserpic Acid Methyl Ester

1.2 Other means of identification

Product number -
Other names Reserpic acid, methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2901-66-8 SDS

2901-66-8Downstream Products

2901-66-8Relevant articles and documents

CHEMOTHERAPEUTIC FOR INDUCING AN MSH2-DEPENDENT APOPTOTIC PATHWAY

-

Page/Page column 18, (2009/04/25)

A method of treating cancer in a subject in need thereof comprises administering said subject reserpine, yohimbine, an analog thereof, or a pharmaceutically acceptable salt or prodrug thereof, in an amount effective to treat the cancer. Compounds and compositions useful for carrying out the method are also described.

Process for the Semisynthesis of Deserpidine

-

Page/Page column 3, (2008/12/07)

The present invention relates to an efficient procedure for the synthesis of deserpidine (Ia), starting from reserpic acid lactone (II) via the intermediate 11-O-demethyl reserpic acid lactone (III).

Regiospecific and stereoselective syntheses of (±)-reserpine and (-)-reserpine

Stork, Gilbert,Tang, Peng Cho,Casey, Michael,Goodman, Burton,Toyota, Masahiro

, p. 16255 - 16262 (2007/10/03)

Full details of three approaches to an entirely regio- and Stereoselective synthesis of the well-known target reserpine are described, culminating in a total synthesis which efficiently meets these requirements.

A PROCESS FOR THE SEMISYNTHESIS OF DESERPIDINE

-

Page/Page column 6, (2010/02/14)

The present invention relates to an efficient procedure for the synthesis of deserpidine (Ia), starting from reserpic acid lactone (II) via the intermediate 11-O-demethyl reserpic acid lactone (III).

Total synthesis of (-)-reserpine using the chiron approach

Hanessian, Stephen,Pan, Jingwen,Carnell, Andrew,Bouchard, Herve,Lesage, Luc

, p. 465 - 473 (2007/10/03)

A highly stereocontrolled synthesis of ring D/E precursor to reserpine has been developed starting from (-)-quinic acid as a chiral template. The total synthesis of (-)-reserpine is described through the cyclization of an immonium lactam intermediate.

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