291744-01-9Relevant articles and documents
Synthesis of 2-Arylpyrazolo[1,5- a ]pyridines by Suzuki-Miyaura Cross-Coupling Reaction
Umei, Kentaro,Nishigaya, Yosuke,Kamiya, Megumi,Kohno, Yasushi,Seto, Shigeki
, p. 3221 - 3230 (2015/10/19)
Convenient access to a variety of 2-arylated pyrazolo[1,5-a]pyridine via pyrazolo[1,5-a]pyridine-2-yl triflate using the Suzuki-MiyauraA AA cross-coupling reaction is described. Fifteen 2-arylpyrazolo[1,5-a]pyridine derivatives were synthesized in 52-95% yields.
The identification of pyrazolo[1,5-a]pyridines as potent p38 kinase inhibitors
Cheung, Mui,Harris, Philip A.,Badiang, Jennifer G.,Peckham, Gregory E.,Chamberlain, Stanley D.,Alberti, Michael J.,Jung, David K.,Harris, Stephanie S.,Bramson, Neal H.,Epperly, Andrea H.,Stimpson, Stephen A.,Peel, Michael R.
scheme or table, p. 5428 - 5430 (2009/06/18)
A series of pyrazolo[1,5-a]pyridine derivatives was designed and synthesized as novel potent p38 kinase inhibitors. Our approaches towards improving in vitro metabolism and in vivo pharmacokinetic properties of the series are described.
Fused pyrazole derivatives bieng protein kinase inhibitors
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, (2008/06/13)
Compounds of Formula (I): salts or solvates or physiologically functional derivatives thereof, wherein Z is CH or N, and R1, (R2, and R4 are various substituent groups, are protein kinase inhibitors.
Pyrazolopyridines
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, (2008/06/13)
The invention provides the compounds of formula (I) wherein: R0and R1are independently selected from H, halogen, C1-6alkyl, C1-6alkoxy, or C1-6alkoxy substituted by one or more fluorine atoms; R2