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4-(1-ethyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 293760-29-9 Structure
  • Basic information

    1. Product Name: 4-(1-ethyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
    2. Synonyms: 1,2,5-oxadiazol-3-amine, 4-(1-ethyl-1H-benzimidazol-2-yl)-
    3. CAS NO:293760-29-9
    4. Molecular Formula: C11H11N5O
    5. Molecular Weight: 229.2379
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 293760-29-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 462.2°C at 760 mmHg
    3. Flash Point: 233.4°C
    4. Appearance: N/A
    5. Density: 1.51g/cm3
    6. Vapor Pressure: 1E-08mmHg at 25°C
    7. Refractive Index: 1.751
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 4-(1-ethyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-(1-ethyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine(293760-29-9)
    12. EPA Substance Registry System: 4-(1-ethyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine(293760-29-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 293760-29-9(Hazardous Substances Data)

293760-29-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 293760-29-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,3,7,6 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 293760-29:
(8*2)+(7*9)+(6*3)+(5*7)+(4*6)+(3*0)+(2*2)+(1*9)=169
169 % 10 = 9
So 293760-29-9 is a valid CAS Registry Number.

293760-29-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(1-ethylbenzimidazol-2-yl)-1,2,5-oxadiazol-3-amine

1.2 Other means of identification

Product number -
Other names 4-(1-Ethyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:293760-29-9 SDS

293760-29-9Downstream Products

293760-29-9Relevant articles and documents

4-Aminofurazan-3-carboxylic acid iminoester in reactions with N,O-nucleophiles

Sergievskii,Krasnoshek,Mel'nikova,Tselinskii

, p. 872 - 874 (2002)

Reactions of 4-aminofurazan-3-carboxylic acid iminoester with o-aminophenol and ethylenediamine give rise respectively to 4-(1,3-benzoxazol-2-yl)- and 1-(4,5-dihydro-1H-imidazol-2-yl)-1,2,5-oxadiazol-3-amines, with aminoethanol arises 2-[(Z)-1-amino-1-(4-

A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines

Stepanov, Andrei I.,Astrat'ev, Alexander A.,Sheremetev, Aleksei B.,Lagutina, Nataliya K.,Palysaeva, Nadezhda V.,Tyurin, Aleksei Yu.,Aleksandrova, Nataliya S.,Sadchikova, Nataliya P.,Suponitsky, Kyrill Yu.,Atamanenko, Olga P.,Konyushkin, Leonid D.,Semenov, Roman V.,Firgang, Sergei I.,Kiselyov, Alex S.,Semenova, Marina N.,Semenov, Victor V.

, p. 237 - 251 (2015/03/30)

A series of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines (BIFAs) were prepared in good yields (60-90% for each reaction step) via a novel procedure from aminofurazanyl hydroximoyl chlorides and o-diaminobenzenes. The synthetic sequence was run under mild reaction conditions, it was robust and did not require extensive purification of intermediates or final products. Furthermore, there was no need for protection of reactive moieties allowing for the parallel synthesis of diverse BIFA derivatives. Subsequent biological evaluation of the resulting compounds revealed their anti-proliferative effects in the sea urchin embryo model and in cultured human cancer cell lines. The most active compounds showed 0.2-2 μM activities in both assay systems. The unsubstituted benzene ring of the benzoimidazole template as well as the unsubstituted amino group in the furazan ring were essential prerequisites for the antimitotic activity of BIFAs. Compound 57 bearing the 2-chlorophenyl acetamide substituent at the nitrogen atom of the imidazole ring was the most active molecule in the examined set.

4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: Potent and selective p70S6 kinase inhibitors

Bandarage, Upul,Hare, Brian,Parsons, Jonathan,Pham, Ly,Marhefka, Craig,Bemis, Guy,Tang, Qing,Moody, Cameron Stuver,Rodems, Steve,Shah, Sundeep,Adams, Chris,Bravo, Jose,Charonnet, Emmanuelle,Savic, Vladimir,Come, Jon H.,Green, Jeremy

scheme or table, p. 5191 - 5194 (2010/03/24)

We report herein the design and synthesis of 4-(benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine derivatives as inhibitors of p70S6 kinase. Screening hits containing the 4-(benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine scaffold were optimized for p70S6K potency and selectivity against related kinases. Structure-based design employing an active site homology model derived from PKA led to the preparation of benzimidazole 5-substituted compounds 26 and 27 as highly potent inhibitors (Ki 100-fold selectivity against PKA, ROCK and GSK3.

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