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CAS

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29457-07-6

Ticarcillin Disodium Salt, a carboxypenicillin antibiotic, belongs to the beta-lactam class of antibiotics. It is a white solid substance known for its effectiveness in treating infections caused by gram-negative bacteria, particularly Pseudomonas aeruginosa.

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  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodiumsalt (1:2), (2S,5R,6R)-

    Cas No: 29457-07-6

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  • 29457-07-6 Structure

  • Basic information

    1. Product Name: TICARCILLIN DISODIUM SALT
    2. Synonyms: TIMENTIN;TICAR;TICARCILLIN DISODIUM;(2S,5R,6R)-6-[[(2R)-CARBOXY-3-THIENYLACETYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID DISODIUM SALT;(2S,5S,6R)-6-[[(2R)-CARBOXY-3-THIENYLACETYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3,2,0]HEPT;disodium [2S-[2alpha,5alpha,6beta(S*)]]-6-(carboxylato-3-thienylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;3-Thiophenemalonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-, disodium salt, D-(-)- (8CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-[2a,5a,6b(S*)]]-
    3. CAS NO:29457-07-6
    4. Molecular Formula: C15H14N2O6S2*2Na
    5. Molecular Weight: 428.39
    6. EINECS: 249-642-5
    7. Product Categories: Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;antibiotic;Inhibitors
    8. Mol File: 29457-07-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 768.3oC at 760 mmHg
    3. Flash Point: 418.4oC
    4. Appearance: White Solid
    5. Density: N/A
    6. Vapor Pressure: 7.97E-25mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: TICARCILLIN DISODIUM SALT(CAS DataBase Reference)
    11. NIST Chemistry Reference: TICARCILLIN DISODIUM SALT(29457-07-6)
    12. EPA Substance Registry System: TICARCILLIN DISODIUM SALT(29457-07-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 29457-07-6(Hazardous Substances Data)

29457-07-6 Usage

Uses

Used in Pharmaceutical Industry:
Ticarcillin Disodium Salt is used as an injectable antibiotic for the treatment of infections caused by gram-negative bacteria, such as Pseudomonas aeruginosa. Its application is crucial in combating bacterial infections that are resistant to other types of antibiotics, making it a valuable asset in the fight against antibiotic-resistant strains.
Additionally, Ticarcillin Disodium Salt may be used in combination with other antibiotics, such as clavulanic acid, to enhance its effectiveness against a broader range of bacterial infections. This combination therapy can help in reducing the development of antibiotic resistance and improving patient outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 29457-07-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,4,5 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 29457-07:
(7*2)+(6*9)+(5*4)+(4*5)+(3*7)+(2*0)+(1*7)=136
136 % 10 = 6
So 29457-07-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/q;2*+1/p-2/t7-,8-,9+,12-;;/m1../s1

29457-07-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name TICARCILLIN DISODIUM SALT

1.2 Other means of identification

Product number -
Other names Ticarcillin sodium

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:29457-07-6 SDS

29457-07-6Downstream Products

29457-07-6Relevant articles and documents

Preparation method for ticarcillin sodium

-

Paragraph 0028; 0033, (2017/08/29)

The invention discloses a preparation method for ticarcillin sodium. The preparation method comprises the steps that 3-thienylmalonic acid and pivaloyl chloride react in the presence of triethylamine to obtain mixed anhydride; 6-APA and N,O-bis(trimethylsilyl) acetamide react to obtain silylanized 6-APA; then the mixed anhydride reacts with the 6-APA to obtain ticarcillin acid; the ticarcillin acid further reacts with sodium iso-octoate to obtain ticarcillin sodium. The method has the advantages of being mild in reaction condition, simple in operation, simple in post-treatment, friendly to environment, high in product yield and purity and the like.

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