297150-49-3Relevant articles and documents
Enhanced reactivity of electron-deficient enynes in the palladium-catalyzed homo-benzannulation of conjugated enynes
Saito, Shinichi,Chounan, Yukiyasu,Nogami, Tsutomu,Fukushi, Tomoko,Tsuboya, Norie,Yamada, Yasuyuki,Kitahara, Haruo,Yamamoto, Yoshinori
, p. 5350 - 5354 (2007/10/03)
We report the high reactivity of electron-deficient enynes in the homo-benzannulation of conjugated enynes in the presence of Pd(PPh3)4. The introduction of electron-withdrawing groups enabled us to carry out the benzannulation of 1-substituted enynes as well as 1,2- and 2,4-disubstituted enynes. Polysubstituted benzenes were prepared in a highly regioselective manner in good to excellent yields.