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4-(4-Morpholino)-3-nitrobenzaldehyde is a chemical compound characterized by its molecular formula C10H10N2O4. It is a yellow-colored solid that features a benzaldehyde group, a morpholine ring, and a nitro group, which together confer its unique properties and reactivity in chemical reactions. 4-(4-MORPHOLINO)-3-NITROBENZALDEHYDE is primarily recognized for its role as a precursor in the synthesis of complex organic molecules and serves as a building block in the production of pharmaceuticals and agrochemicals.

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  • 300541-91-7 Structure
  • Basic information

    1. Product Name: 4-(4-MORPHOLINO)-3-NITROBENZALDEHYDE
    2. Synonyms: 4-(4-MORPHOLINO)-3-NITROBENZALDEHYDE;4-MORPHOLIN-4-YL-3-NITROBENZALDEHYDE;4-MORPHOLINO-3-NITROBENZALDEHYDE;4-MORPHOLINO-3-NITROBENZENECARBALDEHYDE;ASISCHEM R22738;4-(4-Morpholinyl)-3-nitrobenzaldehyde, 96%;**DISCONTINUED** 4-(4-Morpholinyl)-3-nitrobenzaldehyde, 96%;3-Nitro-4-morpholinobenzaldehyde
    3. CAS NO:300541-91-7
    4. Molecular Formula: C11H12N2O4
    5. Molecular Weight: 236.22
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 300541-91-7.mol
  • Chemical Properties

    1. Melting Point: 57-59°C
    2. Boiling Point: 431.6°C at 760 mmHg
    3. Flash Point: 214.8°C
    4. Appearance: /
    5. Density: 1.34g/cm3
    6. Vapor Pressure: 1.18E-07mmHg at 25°C
    7. Refractive Index: 1.613
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: -0.58±0.40(Predicted)
    11. Sensitive: Air Sensitive
    12. CAS DataBase Reference: 4-(4-MORPHOLINO)-3-NITROBENZALDEHYDE(CAS DataBase Reference)
    13. NIST Chemistry Reference: 4-(4-MORPHOLINO)-3-NITROBENZALDEHYDE(300541-91-7)
    14. EPA Substance Registry System: 4-(4-MORPHOLINO)-3-NITROBENZALDEHYDE(300541-91-7)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: R36/37/38:Irritating to eyes, respiratory system and skin.;
    3. Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 300541-91-7(Hazardous Substances Data)

300541-91-7 Usage

Uses

Used in Organic Synthesis:
4-(4-Morpholino)-3-nitrobenzaldehyde is used as a precursor in organic synthesis for its ability to participate in various chemical reactions, contributing to the formation of a wide range of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 4-(4-Morpholino)-3-nitrobenzaldehyde is utilized as a building block for the development of new drugs, leveraging its chemical structure to create molecules with potential therapeutic applications.
Used in Agrochemical Production:
Similarly, in agrochemicals, this compound serves as a key component in the synthesis of various products designed to protect and enhance crop yields and quality.
Used as a Research Reagent in Medicinal Chemistry:
4-(4-Morpholino)-3-nitrobenzaldehyde is also employed as a research reagent in the field of medicinal chemistry, where it aids in drug discovery processes by providing a foundation for the creation and testing of new chemical entities.
Used in Drug Discovery:
In the realm of drug discovery, this compound is used to explore its potential in the development of new pharmaceutical agents, taking advantage of its distinctive chemical features to innovate and improve upon existing treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 300541-91-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,0,5,4 and 1 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 300541-91:
(8*3)+(7*0)+(6*0)+(5*5)+(4*4)+(3*1)+(2*9)+(1*1)=87
87 % 10 = 7
So 300541-91-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H12N2O4/c14-8-9-1-2-10(11(7-9)13(15)16)12-3-5-17-6-4-12/h1-2,7-8H,3-6H2

300541-91-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-morpholin-4-yl-3-nitrobenzaldehyde

1.2 Other means of identification

Product number -
Other names 3-nitro-4-morpholinobenzaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:300541-91-7 SDS

300541-91-7Relevant articles and documents

Protecting-group-free amination of halogenated nitrobenzaldehyde with palladium catalyst

Cao, Jing,Feng, Jun Xiang,Wu, Yong Xiang,Tuo, Ya Ya

experimental part, p. 935 - 938 (2011/11/13)

"One-step" method for the synthesis of secondary aliphatic amine substituted nitrobenzaldehyde was developed. In the presence of Pd catalyst, halogenated nitrobenzaldehyde could be smoothly coupled with secondary aliphatic amine to give the target product

PROTEIN KINASE INHIBITOR

-

Page/Page column 41, (2010/11/08)

The present invention provides a protein kinase inhibitor (excluding c-Jun N-terminal kinase inhibitor) which comprises, as an active ingredient, an indazole derivative represented by Formula (I) (wherein R1 represents substituted or unsubstituted aryl or a substituted or unsubstituted heterocyclic group) or a pharmaceutically acceptable salt thereof.

Small molecule thienopyrimidine-based protein tyrosine kinase inhibitors

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Page/Page column 42, (2010/02/15)

Various thienopyrimidine-based analog compounds are able to selectively inhibit the Src family of tyrosine kinases. These compounds are useful in the treatment of various diseases including hyperproliferative diseases, hematologic diseases, osteoporosis, neurological diseases, autoimmune diseases, allergic/immunological diseases, or viral infections.

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