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300731-21-9

isopropyl 6-amino-5-cyano-1',3'-dihydro-2-methyl-2'-oxospiro[4H-pyran-4,3'-(2'H)-indole]-3-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • isopropyl 6-amino-5-cyano-1',3'-dihydro-2-methyl-2'-oxospiro[4H-pyran-4,3'-(2'H)-indole]-3-carboxylate

    Cas No: 300731-21-9

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  • 300731-21-9 Structure

  • Basic information

    1. Product Name: isopropyl 6-amino-5-cyano-1',3'-dihydro-2-methyl-2'-oxospiro[4H-pyran-4,3'-(2'H)-indole]-3-carboxylate
    2. Synonyms: isopropyl 6-amino-5-cyano-1',3'-dihydro-2-methyl-2'-oxospiro[4H-pyran-4,3'-(2'H)-indole]-3-carboxylate
    3. CAS NO:300731-21-9
    4. Molecular Formula: C18H17N3O4
    5. Molecular Weight: 339.34528
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 300731-21-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: isopropyl 6-amino-5-cyano-1',3'-dihydro-2-methyl-2'-oxospiro[4H-pyran-4,3'-(2'H)-indole]-3-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: isopropyl 6-amino-5-cyano-1',3'-dihydro-2-methyl-2'-oxospiro[4H-pyran-4,3'-(2'H)-indole]-3-carboxylate(300731-21-9)
    11. EPA Substance Registry System: isopropyl 6-amino-5-cyano-1',3'-dihydro-2-methyl-2'-oxospiro[4H-pyran-4,3'-(2'H)-indole]-3-carboxylate(300731-21-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 300731-21-9(Hazardous Substances Data)

300731-21-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 300731-21-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,0,7,3 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 300731-21:
(8*3)+(7*0)+(6*0)+(5*7)+(4*3)+(3*1)+(2*2)+(1*1)=79
79 % 10 = 9
So 300731-21-9 is a valid CAS Registry Number.

300731-21-9Downstream Products

300731-21-9Relevant articles and documents

Enantioselective synthesis of spiro[4H-pyran-3,3′-oxindole] derivatives catalyzed by cinchona alkaloid thioureas: Significant water effects on the enantioselectivity

Konda, Swapna,Jakkampudi, Satish,Arman, Hadi D.,Zhao, John C.-G.

, p. 2971 - 2982 (2019)

An efficient stereoselective three-component reaction for the synthesis of functionalized spiro[4H-pyran-3,3′-oxindole] derivatives was realized through an organocatalyzed domino Knoevenagel/Michael/cyclization reaction using a cinchonidine-derived thiourea as the catalyst. Using water as the additive was found to improve the product ee values significantly. Under the optimized conditions, the reactions between isatins, malononitrile, and 1,3-dicarbonyl compounds yield the desired spirooxindole products in good yields (71–92%) and moderate to high ee values (up to 87% ee).

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