300804-91-5

Basic information

• Product Name: AURORA KA-767
• Synonyms: AURORA KA-767;1-(4-methylphenyl)-3-[(4-methylphenyl)amino]-5-(4-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one
• CAS NO: 300804-91-5
• Molecular Formula: C24H21N3O3
• Molecular Weight: 399.44
• Mol File: 300804-91-5.mol

Chemical Properties

• Boiling Point: 599.3°C at 760 mmHg
• Flash Point: 316.2°C
• Appearance: /
• Density: 1.308g/cm³
• Vapor Pressure: 2.54E-14mmHg at 25°C
• Refractive Index: 1.685
• CAS DataBase Reference: AURORA KA-767(CAS DataBase Reference)
• NIST Chemistry Reference: AURORA KA-767(300804-91-5)
• EPA Substance Registry System: AURORA KA-767(300804-91-5)

Safety Data

• Hazardous Substances Data: 300804-91-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C24H21N3O3/c1-16-3-9-19(10-4-16)25-22-15-23(18-7-13-21(14-8-18)27(29)30)26(24(22)28)20-11-5-17(2)6-12-20/h3-15,23,25H,1-2H3/t23-/m1/s1

Upstream product

• 617-35-6 2-oxo-propionic acid ethyl ester 
• 555-16-8 4-nitrobenzaldehdye 
• 106-49-0 p-toluidine 
• 913655-65-9 ethyl (E)-4-(p-nitrophenyl)-2-(p-tolylimino)but-3-enoate 
• 55629-97-5 ethyl (E)-4-(p-nitrobenzyl)-2-oxobut-3-enoate 

Relevant articles and documents

Br?nsted-Acid-Catalyzed Asymmetric Three-Component Reaction of Amines, Aldehydes, and Pyruvate Derivatives. Enantioselective Synthesis of Highly Functionalized γ-Lactam Derivatives

Chiral phosphoric acids are efficient organocatalysts for the asymmetric three-component reaction of amines, aldehydes, and pyruvate derivatives. Simultaneous condensation of amines with both carbonylic compounds followed by a hydrogen bonding activated nucleophilic addition of enamines to imines affords densely functionalized enantioenriched 1,5-dihydro-2H-pyrrol-2-ones. These substrates can be used in subsequent diastereoselective transformations to afford enantiopure γ-lactam derivatives.

Uncatalyzed synthesis of 3-amino-1,5-dihydro-2H-pyrrol-2-ones

Uncatalyzed one-pot pseudo-four-component reaction of ethyl pyruvate, anilines, and aldehydes in n-hexane as solvent, under reflux, affords a variety of 3-amino-1,5-dihydro-2H-pyrrol-2-ones in high yield. n-Hexane is an excellent driving force in preparat

Triethylammonium hydrogen sulfate as a catalyst for the preparation of 1,5-diaryl-3-(arylamino)-1H-pyrrol-2(5H)-one derivatives

Triethylammonium hydrogen sulfate [Et3NH][HSO4]) has been used as an efficient acidic ionic liquid catalyst for the preparation of 1,5-diaryl-3-(arylamino)-1H-pyrrol-2(5H)-ones at room temperature. The present methodology offers the

An efficient synthesis of achiral and chiral cyclic dehydro-α-amino acid derivatives through nucleophilic addition of amines to β,γ- unsaturated α-keto esters

A very simple and efficient synthesis of 3-amino-1,5-dihydro-2H-pyrrol-2- ones is reported. These cyclic dehydro-amino acid derivatives with a stereogenic center at the 5-position were obtained by the addition of two equivalents of amine to β,γ-unsaturate