303085-53-2

Basic information

• Product Name: 3-Pyridazinecarboxaldehyde, 6-chloro- (9CI)
• Synonyms: 3-Pyridazinecarboxaldehyde, 6-chloro- (9CI);3-PYRIDAZINECARBOXYALDEHYDE,6-CHLORO;6-Chloro-3-pyridazinecarboxaldehyde;3-Chloro-6-formylpyridazine;6-chloropyridazine-3-carbaldehyde;6-Chloro-3-formylpyridazine;6-Chloropyridazine-3-carboxaldehyde;6-chloro-3-pyridazinecarboxyaldehyde
• CAS NO: 303085-53-2
• Molecular Formula: C₅H₃ClN₂O
• Molecular Weight: 142.54312
• Product Categories: HALIDE;ALDEHYDE;Building Blocks;Pyridazine
• Mol File: 303085-53-2.mol

Chemical Properties

• Boiling Point: 335℃
• Flash Point: 156℃
• Appearance: /
• Density: 1.432
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.601
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.81±0.10(Predicted)
• CAS DataBase Reference: 3-Pyridazinecarboxaldehyde, 6-chloro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridazinecarboxaldehyde, 6-chloro- (9CI)(303085-53-2)
• EPA Substance Registry System: 3-Pyridazinecarboxaldehyde, 6-chloro- (9CI)(303085-53-2)

Safety Data

• Hazardous Substances Data: 303085-53-2(Hazardous Substances Data)

Usage

Uses

6-chloropyridazine-3-carbaldehyde is a useful reactant for organic synthesis.

InChI:InChI=1/C5H3ClN2O/c6-5-2-1-4(3-9)7-8-5/h1-3H

Upstream product

• 75680-92-1 6-chloro-3-pyridazinecarboxylic acid ethyl ester 
• 5096-73-1 6-chloro-pyridazine-3-carboxylic acid 
• 65202-50-8 methyl 6-chloro-3-pyridazinecarboxylate 
• 223445-04-3 3-chloro-6-vinylpyridazine 

Downstream Products

• 1706439-95-3 3-chloro-6-(difluoromethyl)pyridazine 
• 1011487-94-7 (6-chloropyridazin-3-yl)methanol 
• 5096-73-1 6-chloro-pyridazine-3-carboxylic acid 

Relevant articles and documents

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The application relates to a compound of Formula (I) : or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of GLP-1 receptor, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which GLP-1 receptor plays a role.

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SULFONE PYRIDINE ALKYL AMIDE-SUBSTITUTED HETEROARYL COMPOUNDS

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BENZAMIDE CGRP RECEPTOR ANTAGONISTS

The present invention is directed to benzamide compounds which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS

A compound of the formula (I), or a pharmaceutically-acceptable salt, or in-vivo hydrolysable ester thereof: (I)wherein in (I) C is for example wherein A and B are independently selected from i) ii) and m is 1 or 2;R2b and R6b, R2a and R6a, R3a and R5a, are for example selected from H, F, OMe and Me;R2b' and R6b', R2a' and R6a', R3a', R5a' are for example selected from H, OMe and Me;R1a is for example optionally substituted (1-10C)alkyl;R1b is for example selected from NR5C(=W)R4, a) , or b) wherein HET-1 is for example isoxazolyl and HET-2 is for example triazolyl or tetrazolyl.Methods for making compounds of the formula (I), compositions containing them and their use as antibacterial agents are also described.

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A compound of the formula: wherein Ar is optionally substituted phenyl, etc.; n is 0, 1 or 2; R1is hydogen atom, optionally substituted alkyl, etc.; R2and R3are independently optionally substituted alkyl, etc.; R4and R5are independently hydrogen atom or optionally substituted alkyl; R6is hydrogen atom, hydroxy or alkyl; or a pharmaceutically acceptable salt thereof is useful as a medicament for treating retinal degenerative disorders and the like.