Reactions with Betaines, XXIII. Reactions of Nitrogen- and Sulphur-Betaines with Reactive Halides
Trimethylammonium acetic betain (1) reacts with phenacyl bromide and ethyl bromoacetate, respectively, to give the ester bromides 2 and 7.These can be hydrolyzed with aqueous sodium hydrogencarbonate at 20 deg C to yield besides 1 both C-benzoyl-methanol (3) and the glycolic acid ester 8, respectively.The reaction can also be performed in one step by reacting the betain (1) (with can act as a base) in a double molar ratio with the active halide. - Keywords: Trimethylammonium acetic acid betain; Trimethylammonium acetic acid phenacyl ester bromide; Trimethylammonium acetic acid acetoxy ethyl ester bromide; Phenacyl alcohol; Ethyl glycolate
Wittmann, Helga,Ziegler, Erich
p. 103 - 112
(2007/10/02)
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