303761-79-7Relevant articles and documents
Synthesis and antimicrobial activity of 2-methyl-5-nitroaniline derivatives: A structure-activity relationship study
Lingappa, Mallesha,Kikkeri, N. Mohana,Devaraju, Rakshith,Sreedharamurthy, Satish
, p. 102 - 108 (2012/04/17)
A series of 2-methyl-5-nitroaniline derivatives, 5a-5k and 6a-6f, were synthesized in order to determine their in vitro antimicrobial activity. The chemical structures of the synthesized compounds were confirmed by elemental analyses, UV-visible, FT-IR, 1H NMR and 13C NMR spectral studies. The structure-activity relationships of the synthesized compounds were also discussed. Among the synthesized compounds, 5f, 5d, 6b and 6e showed good antimicrobial activity compared to standard drugs. A series of novel 2-methyl-5-nitroaniline derivatives were synthesized and their antimicrobial efficacy was tested. Among the synthesized compounds, 5f and 5d showed good antimicrobial activity. Copyright