- DERIVATIVES OF 1-PHENYL-1,5-DIHYDRO-BENZO[B] [1.4]DIAZEPINE-2.4-DIONE AS INHIBITORS OF HIV REPLICATION
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Compounds of formula (I) wherein m, R1, R2, R3, X and Y are defined herein, are useful as inhibitors of HIV replication.
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Page/Page column 24; 25
(2011/09/19)
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- HETEROCYCLYC SULFONAMIDES HAVING EDG-I ANTAGONISTIC ACTIVITY
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The invention relates to chemical compounds of formula (I), (Ia) and (Ib) or pharmaceutically acceptable salts thereof, which possess Edg-1 antagonistic activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an anti-cancer effect in a warm-blooded animal, such as man.
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Page/Page column 174
(2008/12/05)
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- Novel fluorine-containing benz-azole derivatives, process for their manufacture and their use as optical brighteners
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Compounds of the general formula STR1 in which X represents a trifluoromethyl group or a fluorine atom, n is 1 or 2, Z is an oxygen atom or a NR grouping, in which R is hydrogen or an optionally substituted alkyl group, the benzo rings optionally containing further nonchromophoric substituents. These compounds may be prepared by reacting the dichloride of 1,4-naphthalene-dicarboxylic acid with 2 mols of an o-aminophenol or of an o-nitroaniline and by subsequently cyclizing the acylamino compound obtained. The products are suitable as optical brighteners.
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