304902-96-3

Basic information

• Product Name: 5-Bromo-2-cyclopropylpyrimidine
• Synonyms: 5-Bromo-2-cyclopropylpyrimidine;2-Cyclopropyl-5-bromopyrimidine
• CAS NO: 304902-96-3
• Molecular Formula: C₇H₇BrN₂
• Molecular Weight: 199
• Mol File: 304902-96-3.mol

Chemical Properties

• Boiling Point: 255℃
• Flash Point: 108℃
• Appearance: /
• Density: 1.657
• PKA: 0.67±0.22(Predicted)
• CAS DataBase Reference: 5-Bromo-2-cyclopropylpyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-cyclopropylpyrimidine(304902-96-3)
• EPA Substance Registry System: 5-Bromo-2-cyclopropylpyrimidine(304902-96-3)

Safety Data

• Hazardous Substances Data: 304902-96-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-2-cyclopropylpyrimidine is used as a reagent for the synthesis of novel glucocorticoid modulators, which are important in the treatment of inflammatory diseases. These modulators help regulate the immune response and reduce inflammation, providing relief to patients suffering from various inflammatory conditions.

InChI:InChI=1S/C7H7BrN2/c8-6-3-9-7(10-4-6)5-1-2-5/h3-5H,1-2H2

Upstream product

• 304902-95-2 5-bromo-2-cyclopropyl-pyrimidine-4-carboxylic acid 
• 23719-80-4 cyclopropylmagnesium bromide 
• 183438-24-6 5-bromo-2-iodopyrimidine 

Downstream Products

• 1375301-91-9 2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine 

Relevant articles and documents

ASK1 INHIBITOR COMPOUNDS AND USES THEREOF

Described herein are compounds, including pharmaceutically acceptable salts, solvates, metabolites, prodrugs thereof, methods of making such compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat non

SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF

Provided are sulfonamide derivatives of a specific chemical structure in which a sulfonamide group having, as a substituent, a phenyl group or a heterocyclic group having a hetero atom(s) as a constituent element(s) is present at its terminal, and pharmaceutically acceptable salts thereof. These compounds are novel compounds having excellent α4 integrin-inhibitory action.

NOVEL HYDANTOIN DERIVATIVES FOR THE TREATMENT OF OBSTRUCTIVE AIRWAY DISEASES

The invention provides compounds of formula (I), wherein R1 and R2 are as defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.

NOVEL COMPOUNDS

The invention provides compounds of formula (I): wherein R1, R2, A, A1 and B are as defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the ph