- Organic synthesis by Twin Screw Extrusion (TSE): Continuous, scalable and solvent-free
-
Mechanochemistry provides a method to reduce or eliminate the use of solvents by carrying out reactions through the grinding of neat reagents. Until recently a significant drawback of this form of synthesis has been the limited ability to scale up. Howeve
- Crawford, Deborah E.,Miskimmin, Clodagh K. G.,Albadarin, Ahmad B.,Walker, Gavin,James, Stuart L.
-
supporting information
p. 1507 - 1518
(2017/05/10)
-
- Solvent-free sonochemistry: Sonochemical organic synthesis in the absence of a liquid medium
-
Sonochemistry, i.e., the application of mechanical energy in the form of sound waves, has recently been recognised for its similarity to mechanochemistry and is now included under the umbrella term of mechanochemistry. Typically, due to the hypothesised c
- Crawford, Deborah E.
-
supporting information
p. 1850 - 1856
(2017/09/27)
-
- Expeditious reaction of ninhydrin with active methylene compounds on montmorillonite K10 clay
-
Ninhydrin reacted expeditiously with thirteen active methylene compounds on montmorillonite K10 clay at room temperature to furnish, in 5 min, a Knoevenagel condensate in one case, aldols in six cases, aldol-derived cyclic hemiketals in three cases, and interesting products in the remaining three cases. Almost identical results were obtained, but faster, when the reactions were carried out in water on steam-bath. The structures of two novel products were also confirmed by single-crystal X-ray diffraction analysis. Graphical abstract: [Figure not available: see fulltext.]
- Chakrabarty, Manas,Mukherji, Ajanta,Arima, Shiho,Harigaya, Yoshihiro,Pilet, Guillaume
-
experimental part
p. 189 - 197
(2010/03/26)
-
- Facile acid-catalyzed condensation of ninhydrin with enols and aromatic compounds and microwave enhanced condensation of ninhydrin with hydroxy aromatic systems in solid state
-
Di- and trihydroxybenzenes, 2,6-dihydroxyacetophenone, α- and β-naphthols and also 3- and 4-hydroxycoumarins and various enols smoothly condense with ninhydrin in HOAc medium giving 2-substituted 1,3-dioxoindanes. Monoarylated products were also obtained
- Kundu, Sandip Kumar,Patra, Amarendra,Pramanik, Animesh
-
p. 604 - 611
(2007/10/03)
-
- Quantitative reaction cascades of ninhydrin in the solid state
-
Crystalline ninhydrin (1) undergoes waste-free solid-state cascade reactions with dimedone, L-proline, three o-phenylenediamines, o-mercaptoaniline, two ureas, three thioureas, and methyl 3-aminocrotonate. The yields are quantitative and give pure crystal
- Kaupp, Gerd,Naimi-Jamal, M. Reza,Schmeyers, Jens
-
p. 594 - 600
(2007/10/03)
-
- REACTION OF TRIFLUOROACETIC ANHYDRIDE ON ADDUCTS DERIVED FROM 1,2,3-INDANETRIONE WITH CYCLIC CH-ACID COMPOUNDS
-
The reaction of the title adducts 3 with trifluoroacetic anhydride-pyridine (which gives smooth dehydration only in cases 3d,f to give 6d,f) is described; the influence of enolization on reactivity is discussed.Compounds 3a-c do not dehydrate but give pyr
- Campagna, Francesco,Carotti, Angelo,Casini, Giovanni,Ferappi, Marcello
-
p. 507 - 514
(2007/10/02)
-