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N-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-N-[2-(methylsulfonyl)phenyl]amine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 305809-45-4 Structure
  • Basic information

    1. Product Name: N-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-N-[2-(methylsulfonyl)phenyl]amine
    2. Synonyms: GW-505524B
    3. CAS NO:305809-45-4
    4. Molecular Formula: C11H15N3O2S
    5. Molecular Weight: 253.3251
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 305809-45-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-N-[2-(methylsulfonyl)phenyl]amine(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-N-[2-(methylsulfonyl)phenyl]amine(305809-45-4)
    11. EPA Substance Registry System: N-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-N-[2-(methylsulfonyl)phenyl]amine(305809-45-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 305809-45-4(Hazardous Substances Data)

305809-45-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 305809-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,5,8,0 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 305809-45:
(8*3)+(7*0)+(6*5)+(5*8)+(4*0)+(3*9)+(2*4)+(1*5)=134
134 % 10 = 4
So 305809-45-4 is a valid CAS Registry Number.

305809-45-4Downstream Products

305809-45-4Relevant articles and documents

Imidazoline derivatives as alpha-1A adrenoceptor ligands

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Page/Page column 11, (2010/02/11)

Compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Such compounds are useful in the treatment of Alpha-1A mediated diseases or conditions such as urinary incontinence.

2-(Anilinomethyl)imidazolines as α1 adrenergic receptor agonists: The discovery of α10 subtype selective 2′-alkylsulfonyl-substituted analogues

Hodson, Stephen J.,Bishop, Michael J.,Speake, Jason D.,Navas III, Frank,Garrison, Deanna T.,Bigham, Eric C.,Saussy Jr., David L.,Liacos, James A.,Irving, Paul E.,Jeffrey Gobel,Sherman, Bryan W.

, p. 2229 - 2239 (2007/10/03)

A series of 2′-alkylthio-2-(anilinomethyl)imidazolines were prepared to examine the effect of the alkyl group size, sulfur oxidation state, and phenyl ring substitution on ligand binding and agonism of α-adrenergic receptor subtypes α1a, α1b, α1d, α2a, and α2c. Binding at all receptor subtypes decreased for compounds in the sulfone oxidation state as compared to their sulfide analogues. While sulfides were generally potent, nonselective agonists, sulfones exhibited α1a subtype selectivity in a cell-based functional assay. Sulfone (32) was 250-7000-fold selective for α1a vs all other subtypes.

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