- N-vinyl amide and preparation method thereof
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The invention relates to N-vinyl amide and a preparation method thereof. The preparation method comprises the following concrete steps: in the presence of triethylamine, reacting acyl chloride with 2-chloroethylamine hydrochloride to obtain corresponding N-(2-chloroethyl)amide, treating the N-(2-chloroethyl)amide with lithium diisopropylamide at room temperature, then adding halogenated hydrocarbon, carrying out a stirring reaction at room temperature for 4 hours, removing the solvent, and performing purification to obtain an N-vinyl amide compound. The preparation method of the invention is simple in synthetic route and uses easily-available raw materials; and the prepared N-vinyl amide compound is a good synthetic intermediate, and has potential biological activity and good application value.
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Paragraph 0013; 0014; 0015
(2019/12/25)
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- Synthesis of cinnamic acid-derived 4,5-dihydrooxazoles
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A range of cinnamic units containing 4,5-dihydrooxazoles was prepared using two different synthetic routes. The first method was based on the transformation of substituted cinnamic or benzoic acids to 2-styryl-4,5- dihydrooxazoles. Several derivatives con
- Kronek, Juraj,Nedelcev, Tomas,Mikulec, Marcel,Kleinova, Angela,Luston, Jozef
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p. 1424 - 1432
(2013/07/26)
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- Structural Revision and Synthesis of Sinharine and Methylsinharine
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An unambiguous synthesis of the published structure for the natural product sinharine (1) showed that the assignment was incorrect. (E)-3-(Methylthio)-N-(2-phenylethyl)propenamide (4) was proposed as an alternative structure and this was confirmed by synt
- Johnson, Wynona M.,Littler, Stuart W.,Strauss, Christopher R.
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p. 751 - 756
(2007/10/02)
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