307496-33-9

Basic information

• Product Name: 2,6-DIFLUOROBENZYLZINC BROMIDE
• Synonyms: 2,6-DIFLUOROBENZYLZINC BROMIDE;2,6-Difluorobenzylzinc bromide 0.5M in THF;2,6-DIFLUOROBENZYLZINC BROMIDE, 0.5M SOL;2,6-difluorobenzylzinc bromide solution;2,6-Difluorobenzylzinc bromide solution 0.5 in THF;2,6-Difluorobenzylzinc bromide 0.5M solution in THF;2,6-Difluorobenzylzinc broMide, 0.5M in THF, packaged under Argon in resealable CheMSeal^t bottles;2,6-Difluorobenzylzinc bromide solution 0.5M in THF
• CAS NO: 307496-33-9
• Molecular Formula: C₇H₅BrF₂Zn
• Molecular Weight: 272.41
• Product Categories: Alkyl;Organozinc Halides;Reike and Organozinc Reagents
• Mol File: 307496-33-9.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: 1 °F
• Appearance: /
• Density: 0.981 g/mL at 25 °C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,6-DIFLUOROBENZYLZINC BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIFLUOROBENZYLZINC BROMIDE(307496-33-9)
• EPA Substance Registry System: 2,6-DIFLUOROBENZYLZINC BROMIDE(307496-33-9)

Safety Data

• Hazard Codes: F,Xn
• Statements: 14-19-22-36/38-40-36/37-11
• Safety Statements: 16-26-33-36-36/37
• RIDADR: UN 2056 3/PG 2
• WGK Germany: 1
• Hazardous Substances Data: 307496-33-9(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2,6-Difluorobenzylzinc bromide is used as a reagent in chemical synthesis for its ability to participate in coupling and catalytic reactions. Its presence can enhance the efficiency of the synthesis process, making it a valuable component in the production of various chemical compounds.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2,6-Difluorobenzylzinc bromide is used as a key intermediate in the synthesis of certain drugs. Its role in facilitating chemical reactions allows for the creation of complex molecules that are otherwise difficult to produce, contributing to the development of new and improved medications.
Used in Research and Development:
2,6-Difluorobenzylzinc bromide is employed as a research tool in the exploration of new chemical pathways and reaction mechanisms. Its unique properties make it an interesting subject for study, potentially leading to the discovery of novel applications and advancements in the field of chemistry.

InChI:InChI=1/C7H5F2.BrH.Zn/c1-5-6(8)3-2-4-7(5)9;;/h2-4H,1H2;1H;/q;;+1/p-1/rC7H5BrF2Zn/c8-11-4-5-6(9)2-1-3-7(5)10/h1-3H,4H2

Downstream Products

• 940891-94-1 5-bromo-2-(2,6-difluorobenzyl)pyridine 
• 940891-87-2 3-chloro-6-(2,6-difluorobenzyl)pyridazine 
• 1471996-92-5 {(S)-6-[(R)-5-cyano-4-(2,6-difluoro-benzyl)-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester 
• 1471996-82-3 {(S)-6-[(R)-4-(2,6-difluoro-benzyl)-7-fluoro-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester 
• 1251845-09-6 methyl 2-(2,6-difluorobenzyl)isonicotinate 
• 927176-33-8 3-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-chloro-6-(2,6-difluorobenzyl)pyridine 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION

The present disclosure relates generally to compounds and pharmaceutical compositions for the selective inhibition of histone lysine demethylase5 (KDM5), particularly KDM5B, and methods of their use in treating conditions and diseases associated with KDM5 activity.