307511-84-8

Basic information

• Product Name: 3-THIOPHENECARBOXYLIC ACID, 2-AMINO-4-[4-(1,1-DIMETHYLETHYL)PHENYL]-, ETHYL ESTER
• Synonyms: 3-THIOPHENECARBOXYLIC ACID, 2-AMINO-4-[4-(1,1-DIMETHYLETHYL)PHENYL]-, ETHYL ESTER;ETHYL 2-AMINO-4-(4-TERT-BUTYLPHENYL)THIOPHENE-3-CARBOXYLATE;2-amino-4-(4-tert-butylphenyl)-3-thiophenecarboxylic acid ethyl ester;2-amino-4-(4-tert-butylphenyl)thiophene-3-carboxylic acid ethyl ester;IVK/9050623;Oprea1_323735;ZINC00137149;AKOS BBS-00000795
• CAS NO: 307511-84-8
• Molecular Formula: C17H21NO2S
• Molecular Weight: 303.42
• Mol File: 307511-84-8.mol

Chemical Properties

• Melting Point: 88-92℃
• Boiling Point: 417.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.134±0.06 g/cm3(Predicted)
• PKA: -0.05±0.14(Predicted)
• CAS DataBase Reference: 3-THIOPHENECARBOXYLIC ACID, 2-AMINO-4-[4-(1,1-DIMETHYLETHYL)PHENYL]-, ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-THIOPHENECARBOXYLIC ACID, 2-AMINO-4-[4-(1,1-DIMETHYLETHYL)PHENYL]-, ETHYL ESTER(307511-84-8)
• EPA Substance Registry System: 3-THIOPHENECARBOXYLIC ACID, 2-AMINO-4-[4-(1,1-DIMETHYLETHYL)PHENYL]-, ETHYL ESTER(307511-84-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 307511-84-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-THIOPHENECARBOXYLIC ACID, 2-AMINO-4-[4-(1,1-DIMETHYLETHYL)PHENYL]-, ETHYL ESTER is used as a reagent for the preparation of novel 4-oxothienopyrimidinyl propanoic acid derivatives. These derivatives hold significant potential in the development of new pharmaceutical compounds, particularly those with therapeutic applications.
Used in Chemical Research:
In the field of chemical research, 3-THIOPHENECARBOXYLIC ACID, 2-AMINO-4-[4-(1,1-DIMETHYLETHYL)PHENYL]-, ETHYL ESTER serves as a key intermediate in the synthesis of various complex organic molecules. Its unique structure allows for further functionalization and modification, enabling the creation of new compounds with diverse properties and potential applications.
Used in Material Science:
3-THIOPHENECARBOXYLIC ACID, 2-AMINO-4-[4-(1,1-DIMETHYLETHYL)PHENYL]-, ETHYL ESTER may also find applications in material science, where its unique structural features can be exploited to develop new materials with specific properties. These materials could be used in a range of industries, from electronics to aerospace, depending on the desired characteristics and performance requirements.

Upstream product

• 943-27-1 4'-t-butylacetophenone 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 1056054-62-6 5-(4-tert-butyl-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one 
• 1082403-96-0 C₁₉H₂₀N₂O₃S 

Relevant articles and documents

Novel 4-oxothienopyrimidinyl propanoic acid derivatives as AMPactivated protein kinase (AMPK) activators

Adenosine 5′-monophosphate (AMP) activated protein kinase (AMPK) is a highly conserved sensor of cellular energy. AMPK has been recognized as a key regulator of mammalian metabolic function and has emerged as an attractive target for the treatment of meta

THIENOPYRIMIDINE DERIVATIVES AS POTASSIUM CHANNEL INHIBITORS

The present invention provides thienopyrimidine compounds which are potasium channels inhibitors. Pharmaceutical compositions comprising the compounds and their use in the treatment of arrhythmia are also provided.