307521-67-1Relevant articles and documents
Binding interaction of quercetin-3-β-galactoside and its synthetic derivatives with SARS-CoV 3CLpro: Structure-activity relationship studies reveal salient pharmacophore features
Chen, Lili,Li, Jian,Luo, Cheng,Liu, Hong,Xu, Weijun,Chen, Gang,Liew, Oi Wah,Zhu, Weiliang,Puah, Chum Mok,Shen, Xu,Jiang, Hualiang
, p. 8295 - 8306 (2007/10/03)
The 3C-like protease (3CLpro) of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is one of the most promising targets for discovery of drugs against SARS, because of its critical role in the viral life cycle. In this study,
Synthesis of novel 3,7-substituted-2-(3',4'-dihydroxyphenyl)flavones with improved antioxidant activity
Van Acker,Hageman,Haenen,Van der Vijgh,Bast,Menge
, p. 3752 - 3760 (2007/10/03)
A series of 3,7-disubstituted-2-(3',4'-dihydroxyphenyl)flavones was synthesized as potential cardioprotective agents in doxorubicin antitumor therapy. The influence of substituents on the 3 and 7 positions of the flavone nucleus on radical scavenging and