- The synthesis and substituent effect of the acid catalyzed hydrolysis of amidosulfites
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The acid-catalyzed hydrolysis of 2-oxo-3-(p-substituted)-phenyl-5-methyl-1, 2,3-oxathiazolidines (1) have been studied in 60% (v/v) 1,4 dioxane-aqueous solutions of perchloric and hydrochloric acids at 10.0 ± 0.05°C. The analysis of the kinetic data by th
- Kutuk, Halil,Bekdemir, Yunus,Turkoz, Nalan
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- Catalytic Amination of Phenols with Amines
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Given the wide prevalence and ready availability of both phenols and amines, aniline synthesis through direct coupling between these starting materials would be extremely attractive. Herein, we describe a rhodium-catalyzed amination of phenols, which provides concise access to diverse anilines, with water as the sole byproduct. The arenophilic rhodium catalyst facilitates the inherently difficult keto–enol tautomerization of phenols by means of π-coordination, allowing for the subsequent dehydrative condensation with amines. We demonstrate the generality of this redox-neutral catalysis by carrying out reactions of a large array of phenols with various electronic properties and a wide variety of primary and secondary amines. Several examples of late-stage functionalization of structurally complex bioactive molecules, including pharmaceuticals, further illustrate the potential broad utility of the method.
- Chen, Kai,Kang, Qi-Kai,Li, Yuntong,Wu, Wen-Qiang,Zhu, Hui,Shi, Hang
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supporting information
p. 1144 - 1151
(2022/02/05)
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- Post-synthesis of Zr-MOR as a robust solid acid catalyst for the ring-opening aminolysis of epoxides
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Zirconosilicate with the MOR topology (Zr-MOR) was successfully prepared using a two-step post-synthesis strategy from pre-dealumination of a H-MOR zeolite and subsequent dry impregnation of Cp2ZrCl2. The incorporated Zr species main
- Tang, Bo,Song, Wei-Chao,Li, Sheng-Yang,Yang, En-Cui,Zhao, Xiao-Jun
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p. 13503 - 13511
(2018/08/21)
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- Heterogeneous borrowing hydrogen reactions with Pd/C and ZnO: Diol scope
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A borrowing hydrogen reaction with different diols was employed for the preparation of complex beta- gamma- or epsilon-amino alcohols from p-toluidine and tetrahydroquinoline with the aim of better understanding the applicability of the Pd/C ZnO heterogeneous catalyst.
- Llabres-Campaner, Pedro J.,Woodbridge-Ortega, Patricia,Ballesteros-Garrido, Rafael,Ballesteros, Rafael,Abarca, Belén
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supporting information
p. 4880 - 4882
(2017/11/29)
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- Efficient solvent-free aminolysis of epoxides under (C4H 12N2)2[BiCl6]Cl·H 2O catalysis
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An efficient and rapid procedure for ring opening of various epoxides with aromatic, aliphatic and heterocyclic amines is developed at room temperature under solvent-free conditions in the presence of (C4H 12N2)2[BiCl6]Cl·H 2O (1 mol %). This catalyst can be reused several times without losing of its activity.
- Lu, Hong-Fei,Sun, Lei-Lei,Le, Wen-Jun,Yang, Fei-Fei,Zhou, Jun-Tao,Gao, Yu-Hua
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experimental part
p. 4267 - 4272
(2012/09/22)
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- Sulfonato-Cu(salen) complex catalyzed N-arylation of aliphatic amines with aryl halides in water
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A water-soluble sulfonato-Cu(salen) complex catalyzed procedure for the N-arylation of simple aliphatic amines, amino alcohols and amino acids in pure water have been developed. A variety of substituted aryl iodides, bromides and electron-deficient chlorides were found to be applicable, and 1,2-disubstituted benzimidazoles could be prepared easily by a cascade amination/condensation process in this catalytic system.
- Wu, Zhiqing,Zhou, Li,Jiang, Zhaoqiong,Wu, Di,Li, Zhengkai,Zhou, Xiangge
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experimental part
p. 4971 - 4975
(2010/11/03)
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- Synthesis and Spectral Behavior of 5-Methyl-3-phenyl-1,3-oxazolidin-2-ones Using NMR
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Heterocyclic compounds of four 5-methyl-3-phenyl-1,3-oxazolidin-2-ones have been synthesized by the reaction of N-2-hydroxyethyl- or N-2-hydroxypropylanilines with phosgene in the presence of pyridine.From the spectral behavior, the title compounds are found to exist in the trans and cis forms.
- Nishiyama, Tomihiro,Matsui, Shigeki,Yamada, Fukiko
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p. 1427 - 1429
(2007/10/02)
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