Optically active dioxatetraazamacrocycles: Chemoenzymatic syntheses and applications in chiral anion recognition
Two new C2 and D2 symmetrical dioxatetraaza 18-membered macrocycles [(R,R)-1 and (S,S,S,S)-2] are efficiently synthesized in enantiomerically pure forms by a chemoenzymatic method starting from (±)-trans-cyclohexane-1,2-diamine. The