- INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS
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The present invention is directed to indazole and azaindazole compounds which are inhibitors of LRRK2 and are useful in the treatment of CNS disorders.
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Page/Page column 262
(2021/01/29)
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- INDAZOLES AS LRRK2 INHIBITORS
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The present invention is directed to indazole compounds which are inhibitors of LRRK2 and are useful in the treatment of CNS disorders.
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Page/Page column 220
(2020/10/09)
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- INDAZOLE DERIVATIVES USEFUL AS MELANIN CONCENTRATING RECEPTOR LIGANDS
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The present invention relates to novel compounds, in particular, novel indazole that may be used as melanin concentrating hormone receptor ligands, methods of preparing such compounds, compositions containing such compounds, and methods of using such compounds to treat MCH related disorders.
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Page/Page column 47-48
(2008/12/05)
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- Azoles. Part 32: Nitroindazole derivatives and their electron affinity
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A modified procedure for the synthesis of the dinitroindazoles 5-8 is described. Treatment of the chloronitro- and dinitroindazoles 1-8 with epichlorohydrin afforded the chlorohydroxypropyl- and epoxypropylindazole derivatives 2a-8a, 1b-5b, 7b and 7c. The structure of the compounds is confirmed by the aid of their IR, 1H and 13C NMR spectra. The electron affinity of the nitroindazole derivatives 1-16 is discussed on the basis of their halfwave potentials and in the combination with their eventual radiosensitizing properties.
- Usarewicz,Wrzeciono,Lukaszewski,Gatniejewska,Peisert
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