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(1R,2S)-FMOC-2-aminocyclohexane carboxylic acid is a derivative of the amino acid lysine, featuring a cyclohexane ring and a fluorenylmethyloxycarbonyl (FMOC) protecting group attached to the amino group. (1R,2S)-FMOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID is widely utilized in organic synthesis and peptide chemistry as a versatile building block for constructing peptide sequences. The FMOC group can be selectively removed under specific conditions, allowing the free amine to participate in further reactions, making it a valuable component in the development of pharmaceuticals and bioconjugates due to its distinctive structure and reactivity.

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  • Cyclohexanecarboxylicacid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (1R,2S)-/ LIDE PHARMA- Factory supply / Best price

    Cas No: 312965-06-3

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  • (1R,2S)-2-[N-BENZYL-N-(MESITYLENESULFONYL)AMINO]-1-PHENYL-1-PROPANOL

    Cas No: 312965-06-3

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  • 312965-06-3 Structure
  • Basic information

    1. Product Name: (1R,2S)-FMOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID
    2. Synonyms: (1R,2S)-FMOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID;(1R,2S)-FMOC-ACHC;(1R,2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclohexanecarboxylic acid
    3. CAS NO:312965-06-3
    4. Molecular Formula: C22H23NO4
    5. Molecular Weight: 365.42
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 312965-06-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 596.9±39.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.29±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 4.76±0.44(Predicted)
    10. CAS DataBase Reference: (1R,2S)-FMOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID(CAS DataBase Reference)
    11. NIST Chemistry Reference: (1R,2S)-FMOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID(312965-06-3)
    12. EPA Substance Registry System: (1R,2S)-FMOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID(312965-06-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 312965-06-3(Hazardous Substances Data)

312965-06-3 Usage

Uses

Used in Pharmaceutical Development:
(1R,2S)-FMOC-2-aminocyclohexane carboxylic acid is used as a key building block in the synthesis of complex peptide-based pharmaceuticals. Its unique cyclohexane ring and FMOC protecting group facilitate the creation of novel peptide sequences with enhanced stability and bioactivity, contributing to the development of innovative therapeutic agents.
Used in Bioconjugate Synthesis:
In the field of bioconjugation, (1R,2S)-FMOC-2-aminocyclohexane carboxylic acid serves as a versatile linker for attaching biologically active molecules to various carriers, such as nanoparticles or polymers. The selective removal of the FMOC group allows for precise control over the conjugation process, enabling the design of targeted drug delivery systems and diagnostic tools with improved specificity and efficacy.
Used in Organic Synthesis:
(1R,2S)-FMOC-2-aminocyclohexane carboxylic acid is employed as a valuable intermediate in the synthesis of various organic compounds, including chiral catalysts, ligands, and natural product analogs. Its cyclohexane ring and FMOC protecting group provide unique structural features that can be exploited for the development of novel synthetic routes and the construction of complex molecular architectures.
Used in Peptide Chemistry:
In peptide chemistry, (1R,2S)-FMOC-2-aminocyclohexane carboxylic acid is utilized as a non-natural amino acid for the synthesis of modified peptides with altered properties. The incorporation of this compound into peptide sequences allows for the exploration of new peptide conformations and functions, with potential applications in drug discovery, materials science, and biotechnology.

Check Digit Verification of cas no

The CAS Registry Mumber 312965-06-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,9,6 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 312965-06:
(8*3)+(7*1)+(6*2)+(5*9)+(4*6)+(3*5)+(2*0)+(1*6)=133
133 % 10 = 3
So 312965-06-3 is a valid CAS Registry Number.

312965-06-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (1R,2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)cyclohexane-1-carboxylic acid

1.2 Other means of identification

Product number -
Other names cis-(N-9-fluorenylmethoxycarbonyl)-2-amino cyclohexane carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:312965-06-3 SDS

312965-06-3Relevant articles and documents

Hairpin folding behavior of mixed α/β-peptides in aqueous solution

Lengyel, George A.,Frank, Rebecca C.,Horne, W. Seth

, p. 4246 - 4249 (2011/06/21)

The invention of new strategies for the design of protein-mimetic oligomers that manifest the folding encoded in natural amino acid sequences is a significant challenge. In contrast to the α-helix, mimicry of protein β-sheets is less understood. We report

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