313957-02-7

Basic information

• Product Name: 2-[4-(4-butylphenyl)-1,3-thiazol-2-yl]-3-(3-ethoxy-4-hydroxyphenyl)acrylonitrile
• Synonyms: 2-[4-(4-butylphenyl)-1,3-thiazol-2-yl]-3-(3-ethoxy-4-hydroxyphenyl)acrylonitrile
• CAS NO: 313957-02-7
• Molecular Formula: C24H24N2O2S
• Molecular Weight: 404.52456
• Mol File: 313957-02-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[4-(4-butylphenyl)-1,3-thiazol-2-yl]-3-(3-ethoxy-4-hydroxyphenyl)acrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(4-butylphenyl)-1,3-thiazol-2-yl]-3-(3-ethoxy-4-hydroxyphenyl)acrylonitrile(313957-02-7)
• EPA Substance Registry System: 2-[4-(4-butylphenyl)-1,3-thiazol-2-yl]-3-(3-ethoxy-4-hydroxyphenyl)acrylonitrile(313957-02-7)

Safety Data

• Hazardous Substances Data: 313957-02-7(Hazardous Substances Data)

Upstream product

• 64356-03-2 2-bromo-1-(4-butylphenyl)ethanone 
• 121-32-4 4-hydroxy-3-ethoxybenzaldehyde 

Relevant articles and documents

Multicomponent Synthesis of Thiazole, Selenazole, Pyrane, and Pyridine Derivatives, Initiated by the Knoevenagel Reaction

(2E,2′E)-3,3′-(Propane-1,3-diyl)bis[oxy(4,1-phenylene)]bis[2-(4-aryl-1,3-thiazol-2-yl)acrylonitriles] and functionally substituted pyridines and fused pyrans containing a 3-[1,3-thi(selen)azol-2-yl]-substituent were synthesized by multicomponent condensations initiated by the Knoevenagel reaction. The structures of 2-amino-5-oxo-4-(1-phenylethyl)-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile and 2-amino-7-hexyloxy-4-cyclohexyl-4H-chromene-3-carborutrile were studied by X-ray diffraction analysis.

Transformation of 4-aryl(heteryl)-2,6-diamino-3,5-dicyano-4H-thiopyrans into substituted acrylonitriles, 1,4-dihydropyridines, 2,3,4,7- tetrahydrothiazolo[3,2-a]pyridine, and 4,7-dihydrothieno[2,3-b]pyridine

Cross-recyclization of 4-aryl(heteryl)-2,6-diamino-3,5-dicyano-4H- thiopyrans with α-bromoketones or alkyl halides formed substituted 3-aryl-2-(4-R-thiazol-2-yl)acrylonitriles, 2-alkylsulfanyl-1,4-dihydropyridines, 2,3,4,7-tetrahydrothiazolo[3,2-a]pyridin