- TYROSINE KINASE NON-RECEPTOR 1 (TNK1) INHIBITORS AND USES THEREOF
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Provided herein is a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein values for the variables (e.g, X11, X22, R11, R22, R33, R44, R55, R66, R77, R88, m, n) are as described herein. Compounds of Formula I, pharmaceutically acceptable salts thereof, pharmaceutical compositions of either of the foregoing, and combinations of any of the foregoing can be used to treat tyrosine kinase non- receptor 1 (TNK1)-mediated diseases, disorders and conditions.
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Paragraph 00333; 00404
(2021/01/23)
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- THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN
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The invention provides a compound of formula (I) (where R1, R1’, R2, R3, X, Y, Z and n are disclosed herein) or a pharmaceutically acceptable salt thereof (s “Diaminoalkylene Compound”); pharmaceutical compositions comprising an effective amount of a Diaminoalkylene Compound; and methods for treating pain, as well as other conditions, comprising administering to an animal in need thereof an effective amount of a Diaminoalkylene Compound.
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Page/Page column 105
(2008/06/13)
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- Sulfonyldihydroimidazopyridinone compounds as 5-hydroxytryptamine-6 ligands
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The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of a central nervous system disorder related to or affected by the 5-HT6 receptor.
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Page/Page column 8
(2008/06/13)
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